Kera Takeshi, Kawai Hisashi, Takahashi Junta, Hirano Hirohiko, Watanabe Yutaka, Fujiwara Yoshinori, Ihara Kazushige, Kim Hunkyung, Obuchi Shuichi
Department of Physical Therapy, Takasaki University of Health and Welfare, Gunma, Japan; Research Team for Human Care, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Research Team for Human Care, Tokyo Metropolitan Institute of Gerontology, Tokyo, Japan.
Gait Posture. 2022 Mar;93:177-182. doi: 10.1016/j.gaitpost.2022.02.001. Epub 2022 Feb 3.
Ground reaction force during sit-to-stand motion is related to lower extremity strength, and such measurements indicating weak muscle strength, may be linked to sarcopenia. We aimed to examine and describe the relationship between sarcopenia and ground reaction force during sit-to-stand motion to develop a diagnostic tool.
Can ground reaction force during sit-to-stand motion help detect sarcopenia?
This study included 627 community-dwelling older adults who were divided into non-sarcopenia and sarcopenia groups to compare ground reaction force parameters. A sit-to-stand force analyzer was used to measure the ground reaction force, power, and time between the minimum and maximum ground reaction force. We assessed the association between sarcopenia and each ground reaction force parameter. Receiver operating characteristic curve analysis was performed with sarcopenia as the dependent variable and ground reaction force-related measurements as independent variables. The probability of predicting sarcopenia was calculated using multiple logistic regression analysis, with sex and age as independent variables, and another receiver operating characteristic analysis was performed using the probability value.
Ground reaction force parameters related to strength and power were lower in the sarcopenia group than in the non-sarcopenia group. Furthermore, we were able to develop a formula to detect sarcopenia using the maximum ground reaction force (area under the curve; 0.906 [95% CI 0.858-0.954] for men and 0.858 [0.808-0.908] for women). The sensitivity and specificity of sarcopenia detection using this formula were 89.7% and 80.5%, respectively, for men and 95.0% and 60.9%, respectively, for women.
Ground reaction force during sit-to-stand motion may reflect low skeletal muscle strength associated with sarcopenia. We were able to develop a method for sarcopenia detection by analyzing the sit-to-stand force required in only one or two sit-to-stand motions, even though it does not measure the skeletal muscle mass directly.
从坐到站动作过程中的地面反作用力与下肢力量相关，而此类表明肌肉力量薄弱的测量结果可能与肌肉减少症有关。我们旨在研究并描述肌肉减少症与从坐到站动作过程中地面反作用力之间的关系，以开发一种诊断工具。
从坐到站动作过程中的地面反作用力能否有助于检测肌肉减少症？
本研究纳入了627名社区居住的老年人，他们被分为非肌肉减少症组和肌肉减少症组，以比较地面反作用力参数。使用一台从坐到站力量分析仪来测量地面反作用力、功率以及最小和最大地面反作用力之间的时间。我们评估了肌肉减少症与每个地面反作用力参数之间的关联。以肌肉减少症为因变量，以与地面反作用力相关的测量值为自变量进行受试者工作特征曲线分析。使用多因素逻辑回归分析，以性别和年龄为自变量，计算预测肌肉减少症的概率，并使用该概率值进行另一项受试者工作特征分析。
肌肉减少症组中与力量和功率相关的地面反作用力参数低于非肌肉减少症组。此外，我们能够开发出一个使用最大地面反作用力来检测肌肉减少症的公式（曲线下面积；男性为0.906[95%CI0.858 - 0.954]，女性为0.858[0.808 - 0.908]）。使用该公式检测肌肉减少症的敏感性和特异性，男性分别为89.7%和80.5%，女性分别为95.0%和60.9%。
从坐到站动作过程中的地面反作用力可能反映了与肌肉减少症相关的低骨骼肌力量。我们能够通过分析仅一两个从坐到站动作所需的力量来开发一种检测肌肉减少症的方法，尽管它不能直接测量骨骼肌质量。
