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患者和医生对非侵入性诊断心血管成像技术的偏好:一项离散选择实验。

Patient and physician preferences for non-invasive diagnostic cardiovascular imaging technologies: a discrete choice experiment.

作者信息

Bertrand Thomas, Bartlett-Esquilant Gillian, Fischer Kady, Friedrich Matthias G

机构信息

Department of Family Medicine, McGill University, 5858 Côte-des-Neiges Road, Montreal, QC, H3S 1Z1, Canada.

Departments of Medicine and Diagnostic Radiology, Research Institute of the McGill University Health Center, 1001 Decarie Boulevard, Montreal, QC, H4A 3J1, Canada.

出版信息

J Patient Rep Outcomes. 2022 Feb 19;6(1):15. doi: 10.1186/s41687-022-00419-0.

Abstract

PURPOSE

Diagnostic imaging techniques have to be selected for their accuracy, efficiency, cost-efficiency, and impact on outcome. But beyond that, the choice of non-invasive cardiovascular imaging tests for diagnosing coronary artery disease also has to respect patient safety and comfort. In this study, we investigated patient and physician preference in relation to the choice of cardiovascular imaging tests.

RESULTS

A total of 211 subjects (148 cardiac patients and 63 physicians) were enrolled and completed a discrete choice experiment. Tests and modalities were deconstructed into 6 attributes (risks and side effects, diagnostic accuracy, patient out-of-pocket cost, type of procedure, type of scanner and test duration). A Sawtooth software choice-based conjoint analysis with hierarchical Bayes estimation was performed and showed the risks and side effects attribute was assigned the most relative importance (30%) when considering patients' preference. Patients gave notably high value to tests with milder side effects, while preferring to avoid exposure to ionizing radiation and risks associated the use of pharmacological agents inducing direct coronary arteriolar vasodilation. Physicians allocated more importance to the patient out-of-pocket cost attribute (29%). Both patients and physicians valued tests' risks and side effects, diagnostic accuracy, patient out-of-pocket cost as the three most important attributes, but in diverging order. A market simulation comparing current cardiovascular imaging tests revealed breathing maneuver-enhanced cardiac magnetic resonance had the highest shares of preference in both patients (59.6%) and physicians (32.7%).

CONCLUSION

A patients' preference for a particular cardiovascular imaging test was most determined by the risks and side effects, while physicians prioritized less costly tests for their patients. In shared decision-making with patients, physicians should therefore focus on a balanced discussion of risks and side effects associated with cardiovascular imaging tests. Both, patients and physicians would prefer a cardiovascular MR imaging test using a vasoactive breathing maneuver instead of currently used alternatives that require intravenous contrast agents, pharmacological stress, or radiation.

摘要

目的

必须根据诊断成像技术的准确性、效率、成本效益以及对治疗结果的影响来选择这些技术。但除此之外,选择用于诊断冠状动脉疾病的非侵入性心血管成像检查时,还必须考虑患者的安全性和舒适度。在本研究中,我们调查了患者和医生在心血管成像检查选择方面的偏好。

结果

总共招募了211名受试者(148名心脏病患者和63名医生)并完成了一项离散选择实验。检查和方式被分解为6个属性(风险和副作用、诊断准确性、患者自付费用、检查类型、扫描仪类型和检查持续时间)。使用基于锯齿软件的选择联合分析和层次贝叶斯估计进行分析,结果显示,在考虑患者偏好时,风险和副作用属性被赋予了最高的相对重要性(30%)。患者对副作用较小的检查给予了特别高的评价,同时倾向于避免暴露于电离辐射以及与使用诱导直接冠状动脉小动脉血管扩张的药物相关的风险。医生则更重视患者自付费用属性(29%)。患者和医生都将检查的风险和副作用、诊断准确性、患者自付费用视为三个最重要的属性,但顺序不同。一项比较当前心血管成像检查的市场模拟显示,呼吸动作增强的心脏磁共振成像在患者(59.6%)和医生(32.7%)中的偏好份额最高。

结论

患者对特定心血管成像检查的偏好主要取决于风险和副作用,而医生则优先为患者选择成本较低的检查。因此,在与患者共同决策时,医生应重点对心血管成像检查相关的风险和副作用进行平衡讨论。患者和医生都更喜欢使用血管活性呼吸动作的心血管磁共振成像检查,而不是目前使用的需要静脉注射造影剂、药物负荷试验或辐射的替代检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f5c/8858356/39e548990612/41687_2022_419_Fig1_HTML.jpg

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