一种新型低分子量肝素（OP/LMWH）与人血小板的相互作用。
Interaction of a new low molecular weight heparin (OP/LMWH) with human platelets.
作者信息
Mastacchi R, Barbanti M, Bianchini P, Osima B
出版信息
Agents Actions. 1986 Mar;17(5-6):512-4. doi: 10.1007/BF01965523.
PMID:3518359
Abstract
In vitro platelet proaggregating effect of unfractionated heparin (H) and OP/LMWH were studied with human platelets. OP/LMWH produced a significant less potentiation of ADP and PAF induced aggregation and slightly counteracted the antiaggregating effect of PGI2, in comparison with H. The proaggregating effect of both heparins was neutralized by equal contemporaneous amount of protamine sulfate.
摘要
使用人血小板研究了普通肝素（H）和OP/LMWH的体外血小板促聚集作用。与H相比，OP/LMWH对ADP和PAF诱导的聚集的增强作用明显较小，并且略微抵消了PGI2的抗聚集作用。两种肝素的促聚集作用均被等量的硫酸鱼精蛋白同时中和。
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