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[脊柱畸形患者腰椎骨密度双能X线吸收法(DXA)前后位与侧位测量结果的比较:一项体模研究]

[Comparison of Frontal and Lateral Measurements of Bone Mineral Density of the Lumbar Spine with Dual-energy X-ray Absorptiometry (DXA) in Spinal Deformity: a Phantom Study].

作者信息

Takeya Mei, Ishida Satoru, Tozawa Mitsuyuki, Inaoka Tsutomu, Terada Hitoshi

机构信息

Department of Central Radiology, Toho University Sakura Medical Center.

Department of Radiology, Toho University Sakura Medical Center.

出版信息

Nihon Hoshasen Gijutsu Gakkai Zasshi. 2022;78(2):171-179. doi: 10.6009/jjrt.780207.

DOI:10.6009/jjrt.780207
PMID:35185096
Abstract

The bone mineral density (BMD) measurement of the lumbar spine with dual-energy X-ray absorptiometry (DXA) has the advantage of being able to detect early changes in BMD, which is usually used for the evaluation of drug therapy. However, DXA is not considered suitable for spinal deformity because it is a two-dimensional measurement. The aims of this study were to compare frontal and lateral measurements with a phantom and to examine the possibility of the evaluation of lumbar spine BMD in spinal deformity. The values of frontal and lateral measurements were compared when the lumbar phantom was tilted by 10 degrees from 0 to 40 degrees, assuming kyphosis, and when it was tilted by 5 degrees from 0 to 10 degrees to the right and left, assuming scoliosis. We revealed that in the case of kyphosis, the frontal is more accurate, and in the case of scoliosis, the lateral is more accurate; small rotation of subjects on the plane parallel to the image receiving surface could be acceptable. In general, the two-directional BMD measurement is useful for the improvement of the accuracy and may have a potential to measure patients with spinal deformity, which was previously thought to be impossible.

摘要

采用双能X线吸收法(DXA)测量腰椎骨密度(BMD),其优势在于能够检测到BMD的早期变化,该方法通常用于评估药物治疗效果。然而,由于DXA是二维测量,所以它被认为不适用于脊柱畸形的情况。本研究的目的是使用模型比较前后位和侧位测量,并探讨在脊柱畸形中评估腰椎BMD的可能性。假设脊柱后凸,当腰椎模型从0度到40度倾斜10度时,以及假设脊柱侧凸,当腰椎模型从0度到10度向左右两侧各倾斜5度时,比较前后位和侧位测量值。我们发现,在后凸情况下,前后位测量更准确;在侧凸情况下,侧位测量更准确;受试者在与图像接收表面平行的平面上进行小角度旋转是可以接受的。总体而言,双向BMD测量有助于提高准确性,并且有可能对之前被认为无法测量的脊柱畸形患者进行测量。

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