Pan Swagata, Roy Subhadip, Choudhury Neha, Behera Priyanka Priyadarshini, Sivaprakasam Kannan, Ramakrishnan Latha, De Priyadarsi
Polymer Research Centre, Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, India.
Centre for Advanced Functional Materials, Department of Chemical Sciences, Indian Institute of Science Education and Research Kolkata, Mohanpur, India.
Sci Technol Adv Mater. 2022 Feb 14;23(1):49-63. doi: 10.1080/14686996.2021.2018920. eCollection 2022.
Formaldehyde is a well-known industrial material regularly used in fishery, vegetable markets, and fruit shops for maintaining their freshness. But due to its carcinogenic nature and other toxic effects, it is very important to detect it in very low concentrations. In recent years, amine-containing fluorescent probes have gained significant attention for designing formaldehyde sensors. However, the major drawbacks of these small molecular probes are low sensitivity and long exposure time, which limits their real-life applications. In this regard, polymeric probes have gained significant attention to overcome the aforementioned problems. Several polymeric probes have been utilized as a coating material, nanoparticle, quartz crystal microbalance (QCM), etc., for the selective and sensitive detection of formaldehyde. The main objective of this review article is to comprehensively describe the recent advancements in formaldehyde sensors based on small molecules and polymers, and their successful applications in various fields, especially in situ formaldehyde sensing in biological systems.
甲醛是一种广为人知的工业材料，常用于渔业、菜市场和水果店以保持其新鲜度。但由于其致癌性和其他毒性作用，检测极低浓度的甲醛非常重要。近年来，含胺荧光探针在设计甲醛传感器方面受到了极大关注。然而，这些小分子探针的主要缺点是灵敏度低和曝光时间长，这限制了它们在实际生活中的应用。在这方面，聚合物探针为克服上述问题受到了极大关注。几种聚合物探针已被用作涂层材料、纳米颗粒、石英晶体微天平（QCM）等，用于选择性和灵敏地检测甲醛。这篇综述文章的主要目的是全面描述基于小分子和聚合物的甲醛传感器的最新进展，以及它们在各个领域的成功应用，特别是在生物系统中的原位甲醛传感。
