Riant P, Albengres E, Barre J, Tillement J P
Ann Biol Clin (Paris). 1986;44(1):15-24.
Serum level monitoring of drugs allows an optimal drug therapy, because it can take into account individual pharmacokinetic (and metabolic) variations. Some special conditions in drugs and in patients are highly suggestive of drug monitoring. These include mainly physiological but also pharmacological situations and apply to drugs with low therapeutic indices. However, for some drugs, highly bound to proteins or to blood cells, another more specific measurements will take in the future the place of serum level monitoring.
药物的血清水平监测可实现最佳药物治疗，因为它能考虑到个体药代动力学（及代谢）差异。药物和患者的一些特殊情况强烈提示需要进行药物监测。这些情况主要包括生理状况，但也包括药理状况，适用于治疗指数较低的药物。然而，对于某些与蛋白质或血细胞高度结合的药物，未来将采用另一种更具特异性的测量方法来取代血清水平监测。
