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[血浆置换对遗传性高胆固醇血症患者血浆激素水平的影响]

[Effect of plasmapheresis on plasma hormone levels in patients with hereditary hypercholesterolemia].

作者信息

Khashimov Kh A, Vorontsov V I, Kurdanov Kh A, Konovalov G A, Atakhanov Sh E

出版信息

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR. 1986;9(1):79-83.

PMID:3518741
Abstract

It is shown that plasmapheresis in the volume of 30-46 ml/kg using 2997 cellular separator (IBM) does not significantly reduce testosterone, estradiol, aldosterone, parathyroid hormone and calcitonin concentrations. The initially high level of insulin and C-peptide was reduced, angiotensin-I concentration lowered and somatotropic hormone concentration doubled. It is suggested that plasmapheresis stimulates lipolytic and anabolic processes in the organism.

摘要

结果表明,使用2997型细胞分离器(IBM)进行30 - 46毫升/千克体积的血浆置换,并不会显著降低睾酮、雌二醇、醛固酮、甲状旁腺激素和降钙素的浓度。最初较高水平的胰岛素和C肽有所降低,血管紧张素I浓度下降,生长激素浓度翻倍。提示血浆置换可刺激机体的脂肪分解和合成代谢过程。

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