Xinxiang Medical University, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, Zhengzhou, China.
Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, People's Hospital of Zhengzhou University, Henan University People's Hospital, Zhengzhou, China.
Clin Exp Optom. 2023 May;106(4):395-401. doi: 10.1080/08164622.2022.2038013. Epub 2022 Feb 20.
The research status and hotspots in the field of corneal cross linking (CXL) can benefit clinicians, researchers and the general public.
The purpose of this study was to map the publishing trend on CXL research and explore the research hotspots.
A bibliometric analysis was performed using the Web of Science Core Collection to investigate the publishing trend on CXL research. VOSviewer was used to build the knowledge map to visualise the number of annual publications, distribution of countries and institutions, international cooperation, author productivity, source journals and research hotspots in the field of CXL.
A total of 2061 peer-reviewed articles on CXL research were collected from 2001 to 2020, and the annual research production increased over time. The United States was the country with the largest number of published articles, and the University of Zurich was the most active institution. Hafezi F published the largest number of articles on CXL, while was the journal with the largest number of studies on CXL. The most frequently cited references mainly focus on CXL in the treatment of keratoconus. The keywords were divided in 5 categories: 1) CXL mechanism, 2) ectasia diseases and refractive surgery, 3) corneal biomechanics, 4) efficacy evaluation, 5) treatment of infectious keratitis.
The quantity and quality of articles on CXL were evaluated using bibliometric techniques by extracting the data from the Web of Science Core Collection. The research hotspots could provide insights on CXL research, providing valuable information for clinicians to perform research in this field and find potential partners.
角膜交联 (CXL) 领域的研究现状和热点对临床医生、研究人员和公众都有裨益。
本研究旨在绘制 CXL 研究的出版趋势图，并探讨研究热点。
使用科睿唯安 Web of Science 核心合集数据库对 CXL 研究的出版趋势进行文献计量学分析。VOSviewer 用于构建知识图谱，以可视化年度出版物数量、国家和机构分布、国际合作、作者生产力、来源期刊以及 CXL 领域的研究热点。
共收集到 2001 年至 2020 年间有关 CXL 研究的 2061 篇同行评议文章，且研究成果呈逐年增加趋势。美国发表的文章数量最多，苏黎世大学是最活跃的机构。Hafezi F 在 CXL 方面发表的文章数量最多，而《角膜》（Cornea）是发表 CXL 研究最多的期刊。被引频次最高的参考文献主要集中在 CXL 治疗圆锥角膜方面。关键词分为 5 类：1）CXL 机制，2）扩张性疾病和屈光手术，3）角膜生物力学，4）疗效评估，5）感染性角膜炎的治疗。
通过从科睿唯安 Web of Science 核心合集数据库中提取数据，使用文献计量学技术评估了 CXL 相关文章的数量和质量。研究热点可以为 CXL 研究提供深入了解，为临床医生在该领域开展研究并寻找潜在合作伙伴提供有价值的信息。
