Chen Liwei, Li Renfu, Wang Xinli, Wang Zexin, Lin Xiang, Yang Lu, Yao Yunpeng, Sun Shitao, Li Zhenli, Hao Jinle, Lin Bin, Chen Xueyuan, Xie Lijun
Fujian Provincial Key Laboratory of Screening for Novel Microbial Products, Fujian Institute of Microbiology, Fuzhou, Fujian 350007, P. R. China.
CAS Key Laboratory of Design and Assembly of Functional Nanostructures, and Fujian Key Laboratory of Nanomaterials, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002, P. R. China.
J Phys Chem B. 2022 Mar 3;126(8):1768-1778. doi: 10.1021/acs.jpcb.1c09617. Epub 2022 Feb 21.
Development of new mechanochromic luminescent (MCL) materials from aggregation-induced emission luminogens (AIEgens) has attracted wide attention due to their potential application in multiple areas. However, rational design and crafting of new MCL materials from the simple AIEgens skeleton is still a big challenge because of the undesirable concentration quenching effect. In this study, we have constructed a new class of MCL materials by adding one phenyl as a new rotator and incorporating one pair of electron donor (D) and acceptor (A) into the system of rofecoxib skeleton. This strategy endowed the compounds (-) with tunable emission behavior and some of them with the AIE effect and reversible MCL behavior. These properties may be caused by the highly twisted conformation and loosely molecular packing modes, which were elucidated clearly by analyzing the data of single-crystal X-ray diffraction, powder X-ray diffraction, and differential scanning calorimetry. Further investigation revealed that displayed acidochromic property due to the protonation of the nitrogen atom. Moreover, , as a typical compound, showed its potential applications in the area of anticounterfeiting, pH sensor, and LD-specific bioimaging.
基于聚集诱导发光分子（AIEgens）开发新型机械变色发光（MCL）材料因其在多个领域的潜在应用而备受关注。然而，由于存在不良的浓度猝灭效应，从简单的AIEgens骨架合理设计和制备新型MCL材料仍然是一个巨大的挑战。在本研究中，我们通过添加一个苯基作为新的旋转体，并在罗非昔布骨架体系中引入一对电子供体（D）和受体（A），构建了一类新型MCL材料。该策略赋予了化合物（-）可调的发光行为，其中一些具有AIE效应和可逆的MCL行为。这些性质可能是由高度扭曲的构象和松散的分子堆积模式引起的，通过分析单晶X射线衍射、粉末X射线衍射和差示扫描量热法的数据得以明确阐释。进一步研究表明，由于氮原子的质子化，表现出酸致变色性质。此外，作为典型化合物，在防伪、pH传感器和LD特异性生物成像领域显示出其潜在应用。
