阴道出血作为克里米亚-刚果出血热感染的标志：一例报告。
Vaginal bleeding as a sign of Crimean-Congo hemorrhagic fever infection: a case report.
机构信息
Student Research Committee, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Center of Public Health, Environmental and Occupational Hazards Control, Shahid Beheshti University of Medical Science, Tehran, Iran.
出版信息
J Med Case Rep. 2022 Feb 22;16(1):76. doi: 10.1186/s13256-022-03303-z.
BACKGROUND
Crimean-Congo hemorrhagic fever is a severe vector-borne viral hemorrhagic fever with considerable mortality in humans. This disease is endemic in Afghanistan, and its incidence rate has rapidly increased in recent years. This infection can cause a broad range of hemorrhage manifestations including epistaxis, petechial or purpuric rashes, hematemesis, and melena; however, vaginal bleeding is also reported as a rare manifestation.
CASE PRESENTATION
We report the case of a previously healthy 30-year-old Afghan female of shepherding occupation, with a sudden onset of fever, generalized body pain, epistaxis, and vaginal bleeding. She was admitted to the hospital after 7 days of symptom manifestation, with predominant signs being high fever, vaginal bleeding, and elevated liver enzymes. The serological test result for Crimean-Congo hemorrhagic fever was positive. She was treated with oral ribavirin and discharged with normal parameters.
CONCLUSIONS
People in high-risk professions in endemic areas should be informed that vaginal bleeding is a serious symptom and requires immediate action and, therefore, might be attributed to nongynecologic disorders.
背景
克里米亚-刚果出血热是一种严重的虫媒病毒性出血热，人类死亡率相当高。该病在阿富汗流行，近年来发病率迅速上升。这种感染可引起广泛的出血表现，包括鼻出血、瘀点或瘀斑、呕血和黑便；然而，阴道出血也被报道为一种罕见的表现。
病例介绍
我们报告了一例先前健康的 30 岁阿富汗牧羊女性，突然发热、全身疼痛、鼻出血和阴道出血。她在症状出现 7 天后被送往医院，主要体征为高热、阴道出血和肝酶升高。克里米亚-刚果出血热的血清学检测结果为阳性。她接受了口服利巴韦林治疗后出院，各项参数正常。
结论
应告知流行地区高危职业人群，阴道出血是一种严重的症状，需要立即采取行动，因此可能归因于非妇科疾病。
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