Nagoya University, Department of Orthopaedic Surgery, Nagoya, Japan.
Nagoya University, Department of Orthopaedic Surgery, Nagoya, Japan.
J Orthop Sci. 2023 May;28(3):631-636. doi: 10.1016/j.jos.2022.01.014. Epub 2022 Feb 18.
Distal femur fractures have been reported to have a mortality rate comparable to hip fractures, but the risk is still unknown. Recent studies have reported that low body mass index (BMI) is a risk factor for mortality in the elderly. We investigated the efficacy of low BMI for predicting the risk of mortality in distal femur fractures in patients aged over 65 within 18 months after injury and its impact on postoperative clinical outcomes and mortality.
Data from patients followed for more than six months were obtained from our trauma research group's database. We investigated risk factors for increased mortality using Cox proportional hazards models. We divided the analysed cases into low (<18.5 kg/m) and high (>18.5 kg/m) BMI groups. We adjusted the background characteristics of the groups by patient matching, and evaluated the postoperative mortality, complication rate, and knee society score (KSS).
We identified 216 patients, including 58 (26.9%) with low BMI values. Low BMI was an independent risk factor for mortality in all models (Hazard Ratio: 2.9, p = 0.011). The overall survival rate of the low BMI group at 18 months was significantly lower than that of the high BMI group (70.7% vs. 89.1%; p = 0.003). The complication rates of the low BMI and high BMI groups were not significantly different (33.3% vs. 22.2%; p = 0.283). The mean KSS values at 3, 6, and 12 months in the low BMI group was significantly worse than that in the high BMI group (78.7 ± 16.2 vs. 84.8 ± 13.1; p = 0.035, 82.2 ± 16.9 vs. 89.7 ± 8.9; p = 0.005, 86.4 ± 13.0 vs. 91.4 ± 8.4; p = 0.020, respectively).
Our study indicated that low BMI was independent associated with increased mortality and impaired postoperative functional recovery in distal femur fractures of the elderly patients.
股骨远端骨折的死亡率可与髋部骨折相媲美,但风险仍不清楚。最近的研究报告称,低体重指数(BMI)是老年人死亡的一个危险因素。我们研究了低 BMI 对 65 岁以上患者受伤后 18 个月内远端股骨骨折死亡风险的预测作用及其对术后临床结果和死亡率的影响。
从我们的创伤研究小组的数据库中获取随访时间超过 6 个月的患者数据。我们使用 Cox 比例风险模型研究了增加死亡率的危险因素。我们将分析病例分为低(<18.5kg/m)和高(>18.5kg/m)BMI 组。我们通过患者匹配调整组间的背景特征,并评估术后死亡率、并发症发生率和膝关节协会评分(KSS)。
我们共纳入 216 例患者,其中 58 例(26.9%)为低 BMI 值。低 BMI 是所有模型中死亡的独立危险因素(风险比:2.9,p=0.011)。低 BMI 组的 18 个月总生存率明显低于高 BMI 组(70.7% vs. 89.1%;p=0.003)。低 BMI 组和高 BMI 组的并发症发生率无显著差异(33.3% vs. 22.2%;p=0.283)。低 BMI 组的 KSS 评分在 3、6 和 12 个月时均明显低于高 BMI 组(78.7±16.2 与 84.8±13.1;p=0.035,82.2±16.9 与 89.7±8.9;p=0.005,86.4±13.0 与 91.4±8.4;p=0.020)。
本研究表明,低 BMI 与老年患者股骨远端骨折死亡率增加和术后功能恢复不良独立相关。