α-葡萄糖苷酶抑制剂（BAY m 1099）对II型糖尿病患者餐后血糖和胰岛素的影响。
Effect of an alpha-glucosidase inhibitor (BAY m 1099) on post-prandial blood glucose and insulin in type II diabetics.
作者信息
Joubert P H, Bam W J, Manyane N
出版信息
Eur J Clin Pharmacol. 1986;30(2):253-5. doi: 10.1007/BF00614315.
PMID:3519244
Abstract
The effect of a new alpha-glucosidase inhibitor (BAY m 1099), a 1-deoxynojirimycin derivative, was studied in 10 black patients with Type II diabetes mellitus. It produced significant lowering of blood glucose concentration after standardized maize porridge meals. No significant untoward effects were noted. BAY m 1099 appears to offer potential benefit in the management of Type II diabetics, and more extensive clinical investigation is warranted.
摘要
对10名患有II型糖尿病的黑人患者研究了一种新型α-葡萄糖苷酶抑制剂（BAY m 1099，一种1-脱氧野尻霉素衍生物）的效果。在食用标准化玉米粥餐后，它能显著降低血糖浓度。未观察到明显的不良影响。BAY m 1099似乎在II型糖尿病的治疗中具有潜在益处，因此有必要进行更广泛的临床研究。
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