• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

氨基甲酸乙酯麻醉在生理药理学研究中的适用性。第3部分：其他系统与结论。

Suitability of urethane anesthesia for physiopharmacological investigations. Part 3: Other systems and conclusions.

作者信息

Maggi C A, Meli A

出版信息

Experientia. 1986 May 15;42(5):531-7. doi: 10.1007/BF01946692.

DOI:10.1007/BF01946692
PMID:3519271
Abstract

The suitability of urethane anesthesia for physiopharmacological experiments in various systems is briefly reviewed. Urethane anesthesia appears to be suitable for various types of studies on respiratory function and on reflex activation of motility of the urinary bladder and some sections of the intestinal tract. However, urethane produces a variety of potentially disturbing side-effects at endocrine and renal level.

摘要

简要回顾了氨基甲酸乙酯麻醉在各种系统的生理药理学实验中的适用性。氨基甲酸乙酯麻醉似乎适用于各种类型的呼吸功能研究以及膀胱和部分肠道运动反射激活的研究。然而，氨基甲酸乙酯在内分泌和肾脏水平会产生各种潜在的干扰性副作用。

相似文献

1
Suitability of urethane anesthesia for physiopharmacological investigations. Part 3: Other systems and conclusions.氨基甲酸乙酯麻醉在生理药理学研究中的适用性。第3部分：其他系统与结论。
Experientia. 1986 May 15;42(5):531-7. doi: 10.1007/BF01946692.
2
Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 2: Cardiovascular system.乌拉坦麻醉在各系统生理药理学研究中的适用性。第2部分：心血管系统。
Experientia. 1986 Mar 15;42(3):292-7. doi: 10.1007/BF01942510.
3
Suitability of urethane anesthesia for physiopharmacological investigations in various systems. Part 1: General considerations.氨基甲酸乙酯麻醉在各种系统生理药理学研究中的适用性。第1部分：一般考虑因素。
Experientia. 1986 Feb 15;42(2):109-14. doi: 10.1007/BF01952426.
4
The role of calcium in the release of neurotransmitter substances and hormones.钙在神经递质物质和激素释放中的作用。
Pharmacol Rev. 1970 Sep;22(3):389-428.
5
Ovulation blocking actions of urethane in the rat.氨基甲酸乙酯对大鼠排卵的阻断作用。
Endocrinology. 1972 Jul;91(1):87-94. doi: 10.1210/endo-91-1-87.
6
The Suitability of Propofol Compared with Urethane for Anesthesia during Urodynamic Studies in Rats.丙泊酚与氨基甲酸乙酯用于大鼠尿动力学研究麻醉的适用性比较
J Am Assoc Lab Anim Sci. 2016 Jan;55(1):89-94.
7
The influence of urethane on ovulation in the rat.氨基甲酸乙酯对大鼠排卵的影响。
Endocrinology. 1972 Jun;90(6):1594-9. doi: 10.1210/endo-90-6-1594.
8
Stimulation of the hypothalamic-pituitary-adrenal axis and inhibition of growth hormone release via increased central noradrenaline neuronal activity by urethane anaesthesia in the rat: blockade by clonidine.
Aust J Biol Sci. 1987;40(1):91-6.
9
The effects of halothane on ovulation in the rat.氟烷对大鼠排卵的影响。
Experientia. 1973;29(7):880-1. doi: 10.1007/BF01946342.
10
URETHANE ANESTHESIA AND PITUITARY-ADRENAL FUNCTION IN THE RAT.氨基甲酸乙酯麻醉与大鼠垂体-肾上腺功能
J Pharm Pharmacol. 1964 Sep;16:603-10. doi: 10.1111/j.2042-7158.1964.tb07519.x.

引用本文的文献

1
Exploring the multiple effects of nifedipine and captopril administration in spontaneously hypertensive rats through pharmacokinetic-pharmacodynamic analyses.通过药代动力学-药效学分析探索硝苯地平和卡托普利对自发性高血压大鼠的多种作用。
Pharmacol Res Perspect. 2024 Aug;12(4):e1249. doi: 10.1002/prp2.1249.
2
Reflex voiding in rat occurs at consistent bladder volume regardless of pressure or infusion rate.在大鼠中，反射性排空发生在膀胱容量一致的情况下，而与压力或输注率无关。
Neurourol Urodyn. 2023 Sep;42(7):1532-1546. doi: 10.1002/nau.25243. Epub 2023 Jul 9.
3
The effect of urethane and MS-222 anesthesia on the electric organ discharge of the weakly electric fish Apteronotus leptorhynchus.

本文引用的文献

1
Contributions to the physiology of the lungs: Part I. The bronchial muscles, their innervation, and the action of drugs upon them.对肺生理学的贡献：第一部分。支气管肌肉、其神经支配以及药物对它们的作用。
J Physiol. 1903 Mar 16;29(2):97-173. doi: 10.1113/jphysiol.1903.sp000947.
2
THE EFFECTS OF ANAESTHESIA INDUCED BY URETHANE OR PHENOBARBITONE UPON THE DISTRIBUTION OF PERIPHERAL CATECHOL AMINES IN THE RAT.氨基甲酸乙酯或苯巴比妥诱导的麻醉对大鼠外周儿茶酚胺分布的影响
Br J Pharmacol Chemother. 1965 Jun;24(3):752-8. doi: 10.1111/j.1476-5381.1965.tb01631.x.
3
NERVOUS CONTROL OF MICTURITION.
乌拉坦和 MS-222 麻醉对弱电鱼 Apteronotus leptorhynchus 电鱼放电的影响。
J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2023 May;209(3):437-457. doi: 10.1007/s00359-022-01606-6. Epub 2023 Feb 17.
4
Prolonged inhibition of bladder function is evoked by low-amplitude electrical stimulation of the saphenous nerve in urethane-anesthetized rats.在乌拉坦麻醉的大鼠中，通过对隐神经进行低幅度电刺激可诱发膀胱功能长时间抑制。
Physiol Rep. 2022 Nov;10(22):e15517. doi: 10.14814/phy2.15517.
5
Spontaneous Multimodal Neural Transmission Suggests That Adult Spinal Networks Maintain an Intrinsic State of Readiness to Execute Sensorimotor Behaviors.自发性多模态神经传递表明，成年脊髓网络保持着执行感觉运动行为的内在准备状态。
J Neurosci. 2021 Sep 22;41(38):7978-7990. doi: 10.1523/JNEUROSCI.0662-21.2021. Epub 2021 Aug 11.
6
Verification and Defined Dosage of Sodium Pentobarbital for a Urodynamic Study in the Possibility of Survival Experiments in Female Rat.戊巴比妥钠在雌性大鼠存活实验中尿动力学研究的验证和定义剂量。
Biomed Res Int. 2020 Jun 11;2020:6109497. doi: 10.1155/2020/6109497. eCollection 2020.
7
Best practices for cystometric evaluation of lower urinary tract function in muriform rodents.用于多态啮齿动物下尿路功能尿动力学评估的最佳实践。
Neurourol Urodyn. 2020 Aug;39(6):1868-1884. doi: 10.1002/nau.24415. Epub 2020 Jun 8.
8
Interneuron NMDA Receptor Ablation Induces Hippocampus-Prefrontal Cortex Functional Hypoconnectivity after Adolescence in a Mouse Model of Schizophrenia.精神分裂症小鼠模型中，青春期后神经元 NMDA 受体缺失导致海马体-前额叶皮层功能连接不足。
J Neurosci. 2020 Apr 15;40(16):3304-3317. doi: 10.1523/JNEUROSCI.1897-19.2020. Epub 2020 Mar 23.
9
Experimental cortical stroke induces aberrant increase of sharp-wave-associated ripples in the hippocampus and disrupts cortico-hippocampal communication.实验性皮质卒中导致海马体中与尖波相关的涟漪异常增加，并破坏皮质-海马体通讯。
J Cereb Blood Flow Metab. 2020 Sep;40(9):1778-1796. doi: 10.1177/0271678X19877889. Epub 2019 Sep 26.
10
Development of a decerebrate model for investigating mechanisms mediating viscero-sympathetic reflexes in the spinalized rat.开发一种去大脑模型，用于研究脊髓损伤大鼠中介导内脏-交感神经反射的机制。
Am J Physiol Heart Circ Physiol. 2019 Jun 1;316(6):H1332-H1340. doi: 10.1152/ajpheart.00724.2018. Epub 2019 Mar 15.
排尿的神经控制
Physiol Rev. 1965 Jul;45:425-94. doi: 10.1152/physrev.1965.45.3.425.
4
URETHANE HYPERGLYCAEMIA AND HYPOTHALAMIC ACTIVATION.氨基甲酸乙酯所致高血糖症与下丘脑激活
Nature. 1964 Nov 28;204:889-91. doi: 10.1038/204889a0.
5
URETHANE ANESTHESIA AND PITUITARY-ADRENAL FUNCTION IN THE RAT.氨基甲酸乙酯麻醉与大鼠垂体-肾上腺功能
J Pharm Pharmacol. 1964 Sep;16:603-10. doi: 10.1111/j.2042-7158.1964.tb07519.x.
6
OBSERVATIONS ON THE SIGNIFICANCE OF 5-HYDROXYTRYPTAMINE IN RELATION TO THE PERISTALTIC REFLEX OF THE RAT.关于5-羟色胺与大鼠蠕动反射关系的意义观察
Br J Pharmacol Chemother. 1964 Aug;23(1):14-33. doi: 10.1111/j.1476-5381.1964.tb01563.x.
7
Response of the chronic gastric fistula rat to histamine.慢性胃瘘大鼠对组胺的反应。
Am J Physiol. 1957 Aug;190(2):221-8. doi: 10.1152/ajplegacy.1957.190.2.221.
8
Effect of anaesthetics and haemorrhage on the release of neurohypophysial antidiuretic hormone.麻醉和出血对神经垂体抗利尿激素释放的影响。
Br J Pharmacol Chemother. 1956 Sep;11(3):236-44. doi: 10.1111/j.1476-5381.1956.tb01060.x.
9
The influence of laboratory anaesthetics on the increased cutaneous vascular permeability responses to histamine and 5-hydroxytryptamine in rats.实验室麻醉剂对大鼠皮肤血管通透性增加对组胺和5-羟色胺反应的影响。
J Pharmacol Methods. 1980 Nov;4(3):231-5. doi: 10.1016/0160-5402(80)90015-7.
10
Relationship of prolactin secretion to dopamine release into hypophysial portal blood and dopamine turnover in the median eminence.催乳素分泌与多巴胺释放进入垂体门脉血液以及正中隆起中多巴胺周转的关系。
Brain Res. 1980 Jul 7;193(1):284-8. doi: 10.1016/0006-8993(80)90968-3.