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简短报告:对感染艾滋病毒的跨性别女性临床样本中的艾滋病毒护理进行特征描述。

Short report: Characterizing HIV care among a clinical sample of transgender women living with HIV.

机构信息

Women's College Research Institute, Toronto, ON, Canada.

University of Michigan School of Social Work, Ann Arbor, Michigan, USA.

出版信息

HIV Med. 2022 Apr;23(4):324-330. doi: 10.1111/hiv.13261. Epub 2022 Feb 22.

Abstract

INTRODUCTION

This study aimed to characterize and identify factors associated with HIV care among transgender (trans) women living with HIV (TWLWH) in two urban centres in Canada.

METHODS

Retrospective data were collected from clinic charts of TWLWH aged 16 years and older across seven family medicine, endocrinology and/or HIV clinics in Montreal and Toronto, Canada, from 2018 to 2019 (n = 86). We assessed the proportion of individuals being ever engaged in HIV care [defined as having any recorded antiretroviral therapy (ART) regimen and/or viral load], current ART use, and most recent viral load (suppressed [<200 copies/ml] vs. unsuppressed) overall and compared across subgroups using χ tests.

RESULTS

All TWLWH in our sample [100.0%, 95% confidence interval (CI): 95.8-100.0%] were engaged in HIV care; most (93.0%, 95% CI: 85.4-97.4%) were currently using ART and most (93.4%, 95% CI: 85.3-97.8%) with complete data (n = 71/76) were virally suppressed. A higher proportion of trans women of colour (100.0%) reported current ART use compared with white trans women (76.9%, p = 0.017). A higher proportion of those with no documented history of injection drug use (IDU; 96.6%) were virally suppressed compared with those with a history of IDU (66.7%, p = 0.022). Although not statistically significant, 96.2% of those currently reporting feminizing hormone use were virally suppressed, compared with 85.0% of those not reporting use (p = 0.202).

CONCLUSIONS

Once engaged in HIV care, TWLWH in Canada appear to have excellent ART use and viral suppression. Findings can be leveraged to identify target populations to enhance HIV care and to further explore the relationship between gender-affirming medical care and HIV care.

摘要

引言

本研究旨在描述并确定加拿大两个城市中心 HIV 阳性跨性别(trans)女性(TWLWH)接受 HIV 护理的特征和相关因素。

方法

2018 年至 2019 年期间,我们从加拿大蒙特利尔和多伦多的七家家庭医学、内分泌学和/或 HIV 诊所的 TWLWH (年龄 16 岁及以上)的临床图表中收集了回顾性数据(n=86)。我们评估了所有个体曾经接受 HIV 护理的比例[定义为接受任何记录的抗逆转录病毒治疗(ART)方案和/或病毒载量]、当前使用的 ART 以及最近的病毒载量(抑制 [<200 拷贝/ml] 与未抑制),总体上并通过 χ 检验比较了不同亚组之间的差异。

结果

我们样本中的所有 TWLWH[100.0%,95%置信区间(CI):95.8-100.0%]均接受了 HIV 护理;大多数(93.0%,95%CI:85.4-97.4%)正在使用 ART,大多数(93.4%,95%CI:85.3-97.8%)具有完整数据(n=71/76)病毒得到抑制。与白人跨性别女性(76.9%,p=0.017)相比,更多的跨性别有色人种女性(100.0%)报告当前正在使用 ART。与有注射吸毒史(IDU)的人相比,无 IDU 记录史的人(96.6%)病毒得到抑制的比例更高(p=0.022)。虽然没有统计学意义,但目前报告使用女性激素的人中有 96.2%的人病毒得到抑制,而不报告使用的人中有 85.0%(p=0.202)。

结论

在加拿大,一旦接受 HIV 护理,TWLWH 似乎非常重视 ART 的使用和病毒的抑制。研究结果可用于确定目标人群,以加强 HIV 护理,并进一步探讨性别肯定医疗护理与 HIV 护理之间的关系。

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