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膀胱过度活动症药物:按专科分类的抗胆碱能药物与米拉贝隆对比

Overactive bladder medication: Anticholinergics versus mirabegron by specialty.

作者信息

Sripad Abhishek A, Raker Christina A, Sung Vivian W

机构信息

Division of Urogynecology, Department of Obstetrics & Gynecology, Alpert Medical School of Brown University, Providence, RI, USA.

Warren Alpert Medical School of Brown University, Providence, RI, USA.

出版信息

Urologia. 2022 Nov;89(4):511-516. doi: 10.1177/03915603221076949. Epub 2022 Feb 23.

Abstract

PURPOSE

The primary aim of this study was to identify high prescribing specialties of overactive bladder (OAB) medications for Medicare Part D beneficiaries, and describe prescribing trends by specialty from 2013 to 2017. The secondary aim was to compare the proportion of medication claims by medication class in each specialty.

METHODS

We used the Medicare Part D Provider Public Use File to identify the four highest prescribing specialties from 2013 to 2017. We then compared patterns of OAB medication prescription for beneficiaries over 65 years of age between specialties. The number of medication claims, cost, and region were considered. OAB medications were classified as anticholinergic or mirabegron for additional comparison. The primary outcome was the number of OAB medication claims, and the secondary outcome was the proportion of mirabegron claims of all medication claims.

RESULTS

Primary care providers (PCPs), urology, obstetrics and gynecology (OB/GYNs), and other specialties prescribed the most OAB medications. Total claims increased from 4.06 million in 2013 to 4.51 million in 2017. Mirabegron increased from 65,520 to 892,996 claims. PCPs prescribed the most OAB medications. Urologists had the highest proportion of mirabegron prescribing (19.6%), with an increased odds of mirabegron prescribing compared to OBGYNs (aOR 1.18, 95% CI 1.16-1.19). Compared to OBGYNs, PCPs, and other specialties demonstrated decreased odds of prescribing mirabegron (aOR 0.92 with 95% CI 0.91-0.93, and aOR 0.90 with 95% CI 0.88-0.91, respectively).

CONCLUSION

In Medicare Part D beneficiaries, PCPs prescribed the most OAB medications between 2013 and 2017. Urologists were most likely to prescribe mirabegron.

摘要

目的

本研究的主要目的是确定医疗保险D部分受益人的膀胱过度活动症(OAB)药物高处方专科,并描述2013年至2017年各专科的处方趋势。次要目的是比较各专科中按药物类别划分的药物索赔比例。

方法

我们使用医疗保险D部分提供者公共使用文件来确定2013年至2017年处方量最高的四个专科。然后,我们比较了65岁以上受益人在各专科之间的OAB药物处方模式。考虑了药物索赔数量、成本和地区。OAB药物被分类为抗胆碱能药物或米拉贝隆以进行进一步比较。主要结局是OAB药物索赔数量,次要结局是米拉贝隆索赔占所有药物索赔的比例。

结果

初级保健提供者(PCP)、泌尿外科、妇产科(OB/GYN)和其他专科开出的OAB药物最多。总索赔量从2013年的406万增加到2017年的451万。米拉贝隆的索赔量从65520增加到892996。PCP开出的OAB药物最多。泌尿科医生开出米拉贝隆的比例最高(19.

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