Petsche H, Vollmer R
Wien Klin Wochenschr. 1978 May 26;90(11):361-7.
The paper is a review of the progress made over the past years in the understanding of electrical processes occurring during epileptic seizures as elicited by the local application of penicillin. The events at the cellular level of the neocortex are discussed, as well as cortico-subcortical relationships and microtopography of the seizure patterns. The increased excitability under penicillin induces a great number of feedback processes, the electrical effects of which become visible in the seizure EEG with its high degree of organization. Neocortical architectonics is of great importance for the shape of the potentials and their distribution. Seizure patterns of different shape are found in the different layers of the cortex.
本文回顾了过去几年在理解青霉素局部应用引发癫痫发作时所发生的电生理过程方面取得的进展。文中讨论了新皮质细胞水平的事件,以及皮质 - 皮质下关系和癫痫发作模式的微地形学。青霉素作用下兴奋性的增加引发了大量反馈过程,其电效应在具有高度组织性的癫痫发作脑电图中可见。新皮质结构对于电位的形态及其分布非常重要。在皮质的不同层中发现了不同形状的癫痫发作模式。