Department of Nephrology, Shanghai Fourth People's Hospital, Shanghai 200434, China.
Exp Biol Med (Maywood). 2022 May;247(10):815-821. doi: 10.1177/15353702221077937. Epub 2022 Feb 24.
Chronic kidney disease (CKD) seriously affects the quality of life and survival time of patients, and even affects social and national economic development. In China, how to effectively control the disease process of CKD outpatients has not been determined. A retrospective analysis was made to 100 patients with CKD. Fifty patients treated with traditional clinical treatment were in the control group, and the other fifty patients treated with multidisciplinary team (MDT) clinical treatment were in the MDT group. The prognosis of the two groups after treatment was compared, including glomerular filtration rate (GFR), number of renal replacement treatments, and mortality, to evaluate the actual effect of MDT clinic. CKD patients in the MDT group received the MDT clinic for 24 months. There was no significant difference between GFR and serum creatinine level before treatment, and the quality of life was significantly higher than before. In the control group, the GFR declined more dramatically, the serum creatinine level was higher, and the quality of life was lower than before ( < 0.05). The frequency of renal replacement therapy and mortality in the MDT group were significantly lower than those in the control group ( < 0.05). MDT clinic can effectively improve the prognosis of patients with CKD, delay kidney disease progression, and reduce mortality.
慢性肾脏病(CKD)严重影响患者的生活质量和生存时间,甚至影响社会和国家的经济发展。在中国,如何有效控制CKD 门诊患者的病情进程尚未确定。本研究对 100 例 CKD 患者进行回顾性分析,其中 50 例接受传统临床治疗的患者设为对照组,另 50 例接受多学科团队(MDT)临床治疗的患者设为 MDT 组。比较两组患者治疗后的预后,包括肾小球滤过率(GFR)、肾脏替代治疗次数和死亡率,以评估 MDT 临床的实际效果。CKD 患者在 MDT 组接受 MDT 临床治疗 24 个月。治疗前 GFR 和血清肌酐水平无显著差异,生活质量明显高于治疗前。在对照组中,GFR 下降更明显,血清肌酐水平更高,生活质量低于治疗前(<0.05)。MDT 组肾脏替代治疗的频率和死亡率明显低于对照组(<0.05)。MDT 临床可有效改善 CKD 患者的预后,延缓肾脏病进展,降低死亡率。