关注膳食钠、钾、磷、镁和钙在慢性肾脏病进展中的潜在作用。
Focus on the Possible Role of Dietary Sodium, Potassium, Phosphate, Magnesium, and Calcium on CKD Progression.
作者信息
Mazzaferro Sandro, de Martini Natalia, Cannata-Andía Jorge, Cozzolino Mario, Messa Piergiorgio, Rotondi Silverio, Tartaglione Lida, Pasquali Marzia
机构信息
Department of Translational and Precision Medicine, Sapienza University, 00185 Rome, Italy.
Nephrology Unit Policlinico Umberto I Hospital, 00185 Rome, Italy.
出版信息
J Clin Med. 2021 Mar 1;10(5):958. doi: 10.3390/jcm10050958.
The impressive estimated number of chronic kidney disease (CKD) patients in the world justifies any possible effort at implementing preventive measures of disease progression. Renal insufficiency is associated with significant changes in the electrolyte handling and body balance of sodium, potassium, phosphate, magnesium, and calcium, all of which are biologically vital molecules. Dietary habits could contribute significantly to the optimal management of possible derangements. In this review, we examined the available evidence recommending dietary prescriptions for these five elements aiming at reducing CKD progression. Clear evidence that specific dietary prescriptions may halt or reduce CKD progression is lacking. However, some practical recommendations are possible to prescribe the best possible therapy to the individual CKD patient.
据估计，全球慢性肾脏病（CKD）患者数量惊人，这使得任何旨在实施疾病进展预防措施的努力都具有合理性。肾功能不全与电解质处理以及钠、钾、磷、镁和钙的体内平衡的显著变化相关，所有这些都是具有重要生物学意义的分子。饮食习惯对于可能出现的紊乱的最佳管理可能有很大贡献。在本综述中，我们研究了现有证据，这些证据推荐针对这五种元素的饮食处方，旨在减少CKD的进展。目前缺乏明确证据表明特定饮食处方可阻止或减缓CKD的进展。然而，一些实用建议可用于为个体CKD患者开出尽可能最佳的治疗方案。
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