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以社区药房为基础的老年患者跌倒风险药物的靶向药物审查。

Targeted Medication Review of Falls-Risk Medications in Older Patients: A Community Pharmacy-Based Approach.

机构信息

1Middleport Family Health Center, Middleport, New York.

2University at Buffalo, Buffalo, New York.

出版信息

Sr Care Pharm. 2022 Mar 1;37(3):104-113. doi: 10.4140/TCP.n.2022.104.

Abstract

To assess a community pharmacist-provided targeted medication review (TMR) intervention to reduce the number of falls risk-increasing drugs (FRIDs) prescribed to older patients in a community pharmacy setting. A single-site, prospective, interventional pilot study with a historical control group. A single independent community pharmacy in rural Western New York. A convenience sample of subjects was recruited for the intervention group based on the following inclusion criteria: 65 years of age or older, at least one prescription filled at the pharmacy within the past 90 days from date of enrollment in study, enrolled in a local Medicare plan, and prescription for at least one prespecified FRID filled at the pharmacy within 90 days before date of enrollment in study. A control group was collected that had different Medicare Part D plans than the intervention group but otherwise met inclusion criteria and ensured that between all of the control-group patients we included at least one patient prescribed each of the FRID classes that were found in the intervention group. Thirty-six subjects completed the study intervention, and 63 controls were collected. This offset in numbers between groups resulted from intervention subjects taking multiple FRIDs and the control needing to take the same class of FRID, thus one intervention subject may have required multiple control subjects to parallel each FRID class. The intervention involved the community pharmacist assessing the patient's fall risk, then educating the patient on the risks of the FRID he or she was prescribed, and recommending to either replace or discontinue the FRID. The outcomes assessment occurred three months later, with the pharmacist repeating the falls-risk assessment and following up regarding the patient's agreed-upon action plan. The intervention group had 52 FRIDs identified while the control group had 89. The discontinuation rate of FRIDs at three months was significantly higher in the intervention group (7.7% versus 0%; = 0.0172). This study demonstrated that a community pharmacist TMR intervention can reduce the use of FRIDs.

摘要

评估社区药剂师提供的靶向药物审查(TMR)干预措施,以减少社区药剂环境中为老年患者开处方的增加跌倒风险药物(FRID)的数量。这是一项单站点、前瞻性、干预性试点研究,采用历史对照组。在纽约西部农村的一家单一独立社区药房进行。根据以下纳入标准,干预组招募了一组方便的受试者:年龄在 65 岁或以上,在研究登记日期过去 90 天内至少有一次在药房配药,参加当地的医疗保险计划,并且在研究登记日期前 90 天内在药房配药至少有一种规定的 FRID。收集了对照组,他们的医疗保险 D 部分计划与干预组不同,但符合纳入标准,并确保在所有对照组患者中,我们至少包括一名患者开了干预组中发现的每种 FRID 类别的处方。36 名受试者完成了研究干预,收集了 63 名对照。两组之间的数字差异是由于干预组的受试者服用多种 FRID,而对照组需要服用相同类别的 FRID,因此一名干预组的受试者可能需要多名对照组的受试者来平行每种 FRID 类别的药物。干预措施包括社区药剂师评估患者的跌倒风险,然后向患者教育他或她处方的 FRID 风险,并建议替代或停止 FRID。三个月后进行结果评估,药剂师重复跌倒风险评估,并跟踪患者商定的行动计划。干预组有 52 种 FRID 被识别,而对照组有 89 种。干预组在三个月时 FRID 的停药率明显更高(7.7%比 0%;= 0.0172)。这项研究表明,社区药剂师 TMR 干预可以减少 FRID 的使用。

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