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腹腔镜带蒂大网膜瓣脑血运重建术治疗烟雾病 10 年经验

Ten-year experience with laparoscopic pedicled omental flap for cerebral revascularization in patients with Moyamoya disease.

机构信息

Division of Pediatric Surgery, Department of Surgery, Stanford University School of Medicine, 730 Welch Rd, Stanford, Palo Alto, CA 94304, United States.

Division of General Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, United States.

出版信息

J Pediatr Surg. 2022 Nov;57(11):710-715. doi: 10.1016/j.jpedsurg.2022.01.023. Epub 2022 Jan 31.

Abstract

BACKGROUND

The omental flap has numerous extraperitoneal applications in reconstruction and revascularization given its favorable immunologic and angiogenic properties. In patients with Moyamoya disease, cerebral revascularization using a pedicled omental flap has proven to be a viable option following direct revascularization procedures. Historically, harvesting omentum involved laparotomy with the associated risk of complications; herein we describe outcomes from a 10-year experience of laparoscopic harvesting of pedicled omental flap for cerebral revascularization in Moyamoya patients.

METHODS

A retrospective chart review was performed of all patients with Moyamoya disease who underwent laparoscopic omental cerebral transposition between 2011 and 2021. Intraoperative and postoperative complications, length of stay (LOS), and outcomes at follow-up were analyzed.

RESULTS

Twenty-one patients underwent the procedure during the study period. Three intraoperative complications occurred (one segmental transverse colectomy for mesenteric injury, one converted to omental free flap, and one requiring micro anastomosis). Average overall LOS was 6 ± 6 days, with 3 ± 3.5 days in the ICU (mean±SD). Following discharge, complications included epigastric incisional hernia at the graft fascial exit site, recurrent neck pain at subcutaneous tunneling site, and partial scalp necrosis. One patient required subsequent direct bypass seven months after the initial procedure owing to the progression of the disease. All other patients had partial or complete resolution of symptoms.

CONCLUSION

Our retrospective observational study indicates that laparoscopic pedicled omental flap mobilization and transposition is a safe and effective method of indirect cerebral revascularization in patients with Moyamoya disease.

LEVEL OF EVIDENCE

N/A.

摘要

背景

由于其良好的免疫和血管生成特性,网膜瓣在重建和血运重建方面具有许多腹膜外应用。在烟雾病患者中,使用带蒂网膜瓣进行脑血运重建已被证明是直接血运重建后一种可行的选择。历史上,采集网膜需要剖腹手术,存在相关并发症风险;在此,我们描述了 10 年来对烟雾病患者进行腹腔镜带蒂网膜脑移位术以进行脑血运重建的经验结果。

方法

对 2011 年至 2021 年间接受腹腔镜网膜脑移位术的所有烟雾病患者进行了回顾性图表审查。分析了术中及术后并发症、住院时间(LOS)和随访结果。

结果

研究期间共有 21 例患者接受了该手术。术中发生了 3 例并发症(1 例因肠系膜损伤行节段性横结肠切除术,1 例转为网膜游离皮瓣,1 例需要微血管吻合术)。平均总 LOS 为 6±6 天,ICU 为 3±3.5 天(平均值±标准差)。出院后,并发症包括移植物筋膜出口处的上腹切口疝、皮下隧道处的颈部疼痛复发和部分头皮坏死。1 例患者因疾病进展,在初始手术后 7 个月后需要进行直接旁路手术。所有其他患者的症状均部分或完全缓解。

结论

我们的回顾性观察研究表明,腹腔镜带蒂网膜瓣游离和移位是烟雾病患者间接脑血运重建的一种安全有效的方法。

证据水平

N/A。

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