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前尿道成形术后性功能障碍的前瞻性研究:病因、发生率及功能恢复——单中心经验

Prospective study of sexual dysfunction after anterior urethroplasty: Causative factors, incidence, and recovery of function - A single-center experience.

作者信息

Bhowmik Prasenjit, Sharma Gaurav, Sharma Pramod Kumar, Patawari Piyush Kumar, Dey Sumantra, Mandal Soumendranath

机构信息

Department of Urology, Calcutta National Medical College and Hospital, Kolkata, West Bengal, India.

出版信息

Urol Ann. 2022 Jan-Mar;14(1):60-66. doi: 10.4103/ua.ua_24_21. Epub 2021 Sep 25.

DOI:10.4103/ua.ua_24_21
PMID:35197705
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8815360/
Abstract

OBJECTIVES

The objectives of this study were to evaluate the effect of single-stage anterior urethroplasty on sexual function by considering age, stricture length, location, and different surgical techniques. Incidence of postoperative sexual dysfunction (SD) and probability of recovery were also highlighted.

MATERIALS AND METHODS

A total of 115 patients undergoing anterior urethroplasty from February 2016 to June 2020 were evaluated prospectively. Patients were categorized on the basis of age, location, length of stricture as well as surgical techniques. We evaluated three domains of sexual function (erectile, orgasmic, and overall satisfaction) using the International Index of Erectile Function (IIEF) preoperatively and then after 3 months and 6 months postoperatively in follow-up. Pre- and postoperative IIEF values were compared.

RESULTS

The mean age was 41.7 ± 13.9 years. There was a significant decrease in postoperative IIEF score from the preoperative value in older patients (>40 years) along with poor recovery at the 6 month as compared to patients of younger age group (≤40 years). However, there was a significant reduction of sexual function postoperatively in case of longer stricture segment, panurethral stricture, bulbar urethral stricture, dorsal buccal mucosal urethroplasty, and excision-primary anastomosis technique in univariate analysis, but on multivariate analysis, only age was proved to be an independent predictor of SD which was found in a total of 28 patients (24.3%).

CONCLUSION

Overall, anterior urethroplasty does not influence postoperative sexual function, whereas only older patients have a poor outcome. Most of the younger patients recover completely by 6 months.

摘要

目的

本研究的目的是通过考虑年龄、狭窄长度、位置和不同手术技术,评估一期前路尿道成形术对性功能的影响。还强调了术后性功能障碍(SD)的发生率和恢复概率。

材料与方法

对2016年2月至2020年6月期间共115例行前路尿道成形术的患者进行前瞻性评估。根据年龄、位置、狭窄长度以及手术技术对患者进行分类。我们在术前以及术后3个月和6个月随访时使用国际勃起功能指数(IIEF)评估性功能的三个领域(勃起、性高潮和总体满意度)。比较术前和术后的IIEF值。

结果

平均年龄为41.7±13.9岁。与年轻年龄组(≤40岁)患者相比,老年患者(>40岁)术后IIEF评分较术前值显著降低,且6个月时恢复较差。然而,单因素分析显示,在狭窄段较长、全尿道狭窄、球部尿道狭窄、背侧颊黏膜尿道成形术和切除-一期吻合技术的情况下,术后性功能有显著降低,但多因素分析显示,只有年龄被证明是性功能障碍的独立预测因素,共有28例患者(24.3%)出现性功能障碍。

结论

总体而言,前路尿道成形术不影响术后性功能,而只有老年患者预后较差。大多数年轻患者在6个月时完全恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8317/8815360/ed91da2ddf30/UA-14-60-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8317/8815360/bee129accaec/UA-14-60-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8317/8815360/1c268ce8f87c/UA-14-60-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8317/8815360/ed91da2ddf30/UA-14-60-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8317/8815360/bee129accaec/UA-14-60-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8317/8815360/1c268ce8f87c/UA-14-60-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8317/8815360/ed91da2ddf30/UA-14-60-g003.jpg

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本文引用的文献

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The effect of urethral transection on erectile function after anterior urethroplasty.前尿道成形术后尿道横断对勃起功能的影响。
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