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慢性粒细胞白血病患者因白细胞窃血导致的假性低氧血症

Pseudohypoxemia From Leukocyte Larceny in a Patient With Chronic Myelogenous Leukemia.

作者信息

Mirzai Saeid, Andreae Mark, Puttarajappa Chethan

机构信息

Department of Medicine, Alabama College of Osteopathic Medicine, Dothan, USA.

Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, USA.

出版信息

Cureus. 2022 Jan 19;14(1):e21405. doi: 10.7759/cureus.21405. eCollection 2022 Jan.

Abstract

Arterial blood gas (ABG) analysis is a generally reliable and frequently employed test for evaluating blood oxygen content. False readings of low oxygen content are rare but can be expected in specific clinical scenarios such as leukemia patients with marked leukocytosis who can develop "leukocyte larceny," a phenomenon of excess oxygen consumption by leukocytes. Awareness of this phenomenon may lead to early recognition and avoidance of unnecessary diagnostic and therapeutic interventions. This case report presents a patient with marked leukocytosis from chronic myelogenous leukemia whose extubation was briefly delayed due to pseudohypoxemia on ABG measurements.

摘要

动脉血气(ABG)分析是一种评估血液氧含量的普遍可靠且常用的检测方法。低氧含量的错误读数很少见,但在特定临床情况下可能会出现,比如患有明显白细胞增多症的白血病患者,他们可能会发生“白细胞窃氧”现象,即白细胞过度消耗氧气的现象。认识到这种现象可能有助于早期识别并避免不必要的诊断和治疗干预。本病例报告介绍了一名慢性粒细胞白血病导致明显白细胞增多的患者,其拔管因ABG测量出现假性低氧血症而短暂延迟。

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本文引用的文献

1
Leukocyte larceny: a cause of pseudohypoxemia.
Can J Anaesth. 2016 Dec;63(12):1374-1375. doi: 10.1007/s12630-016-0691-1. Epub 2016 Jun 28.
3
Spurious hypoxemia.假性低氧血症
Crit Care Med. 2005 Aug;33(8):1854-6. doi: 10.1097/01.ccm.0000171838.41529.22.

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