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2019年埃塞俄比亚西北部新生儿出生窒息的决定因素:病例对照研究

Determinants of birth asphyxia among newborns in Northwest Ethiopia, 2019: case control study.

作者信息

Jimma Melkamu Senbeta, Abitew Kennean Mekonnen, Chanie Ermias Sisay, GebreEyesus Fisha Alebel, Kelkay Mengistu Mekonnen

机构信息

Department of Nursing, Colleges of Health Science, Assosa University, Ethiopia.

Department of Emergency Medicine and Critical Care Nursing, School of Nursing, Colleges of Medicine and Health Sciences University of Gondar, Ethiopia.

出版信息

Heliyon. 2022 Feb 1;8(2):e08875. doi: 10.1016/j.heliyon.2022.e08875. eCollection 2022 Feb.

Abstract

INTRODUCTION

Birth asphyxia is a condition of impaired gas exchange in newborns when the Apgar score is < 7 in the first 5 min. It accounts 31.6% of all neonatal deaths, and the leading causes of neonatal mortality in Ethiopia. Identifying its determinant factors is very important to prevent the problem.Therefore, this study was aimed at identifying the determinant factors of birth asphyxia among newborns at Benishangul Gumuz region hospital.

METHODS AND MATERIALS

The hospital-based unmatched case-control study was done from March 04 to July 16, 2019 in Benishangul Gumuz Region Hospitals. Total sample size is 275 with 69 cases and 206 controls. Newborns with an Apgar score of less than 7 at 5 min were taken as cases, and those with greater or equal to 7 were taken as controls. All asphyxiated newborns were enrolled as cases, where as in every three-step non-asphyxiated newborns were taken as controls. The data was entered into Epi Info 7 and exported to SPSS for analysis. Bivariable logistic regression analysis was used. Those variables with a p-value <0.05 were identified as significant determinants of birth asphyxia.

RESULTS

In the current study, anemia during pregnancy [AOR = 2.95, 95% CI: (1.02, 8.54)], no ANC visit at all [AOR = 4.26, 95% CI: (1.23,14.7)], prolapsed cord [AOR = 4.52, 95% CI: (1.3, 21)], and low birth weight [AOR = 4.1, 95% CI: (1.11, 15.36] were all determinant factors for birth asphyxia.

CONCLUSION

and Recommendations: The identified determinants of birth asphyxia were anemia during pregnancy, no ANC visit at all, prolapsed cord, cesarean birth, and low birth weight.Based on our study, most of identified determinant factors of birth asphyxia were preventable so, policy makers, clinicians, and other stakeholders need to invest their maximum effort on prevention of birth asphyxia.

摘要

引言

出生窒息是指新生儿在出生后5分钟内阿氏评分<7分时出现的气体交换受损情况。它占所有新生儿死亡的31.6%,是埃塞俄比亚新生儿死亡的主要原因。确定其决定因素对于预防该问题非常重要。因此,本研究旨在确定本尚古勒-古穆兹地区医院新生儿出生窒息的决定因素。

方法和材料

2019年3月4日至7月16日在本尚古勒-古穆兹地区医院开展了一项基于医院的非匹配病例对照研究。总样本量为275例,其中病例69例,对照206例。5分钟时阿氏评分低于7分的新生儿作为病例,评分大于或等于7分的作为对照。所有窒息新生儿均纳入病例组,每三个未窒息新生儿中选取一个作为对照组。数据录入Epi Info 7并导出至SPSS进行分析。采用二元逻辑回归分析。p值<0.05的变量被确定为出生窒息的重要决定因素。

结果

在本研究中,孕期贫血[AOR = 2.95,95%CI:(1.02, 8.54)]、从未进行产前检查[AOR = 4.26,95%CI:(1.23,14.7)]、脐带脱垂[AOR = 4.52,95%CI:(1.3, 21)]和低出生体重[AOR = 4.1,95%CI:(1.11, 15.36)]均为出生窒息的决定因素。

结论与建议

确定的出生窒息决定因素有孕期贫血、从未进行产前检查、脐带脱垂、剖宫产和低出生体重。基于我们的研究,大多数已确定的出生窒息决定因素是可预防的,因此,政策制定者、临床医生和其他利益相关者需要尽最大努力预防出生窒息。

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