继发于重度化脓性汗腺炎的周边溃疡性角膜炎。
Peripheral ulcerative keratitis secondary to severe hidradenitis suppurativa.
作者信息
Dallalzadeh Liane O, Ang Michael J, Beazer Alex P, Spencer Doran B, Afshari Natalie A
机构信息
UC San Diego Viterbi Family Department of Ophthalmology, Shiley Eye Institute, La Jolla, CA, USA.
出版信息
Am J Ophthalmol Case Rep. 2022 Feb 5;25:101403. doi: 10.1016/j.ajoc.2022.101403. eCollection 2022 Mar.
PURPOSE
To describe a unique case of peripheral ulcerative keratitis secondary to isolated, severe hidradenitis suppurativa (HS).
OBSERVATION
A 31-year-old male with HS presented with a red painful right eye with best corrected visual acuity of count fingers at 3 feet with peripheral corneal thinning, inferior descemetocele, and adjacent infiltrate. Work-up revealed negative corneal cultures and positive ANA, ANCA, and rheumatoid factor without other autoimmune or rheumatologic history or symptomatology. He was treated with topical corticosteroids with improvement until he was lost to follow-up before tumor necrosis factor-a inhibitor therapy could be started. Upon re-presentation, he was found to have corneal perforation.
CONCLUSIONS AND IMPORTANCE
Coexistence of inflammatory eye disease and HS is known but rare, and most commonly manifests as anterior uveitis. Here we present a unique case of peripheral ulcerative keratitis secondary to HS and demonstrate the importance of ophthalmologists' familiarly with this systemic disease and its variety of ocular manifestations.
目的
描述一例继发于孤立性重度化脓性汗腺炎（HS）的周边溃疡性角膜炎的独特病例。
观察
一名患有HS的31岁男性出现右眼红肿疼痛，最佳矫正视力为3英尺处数指，伴有周边角膜变薄、下角膜膨出及相邻浸润。检查发现角膜培养阴性，抗核抗体（ANA）、抗中性粒细胞胞浆抗体（ANCA）和类风湿因子阳性，无其他自身免疫或风湿病史及症状。他接受了局部皮质类固醇治疗，病情有所改善，但在开始肿瘤坏死因子-α抑制剂治疗前失访。再次就诊时，发现他有角膜穿孔。
结论与意义
炎症性眼病与HS并存虽已知但罕见，最常见表现为前葡萄膜炎。在此，我们报告一例继发于HS的周边溃疡性角膜炎的独特病例，并证明眼科医生熟悉这种全身性疾病及其各种眼部表现的重要性。
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