Angiosperm Taxonomy Laboratory, Department of Botany, Shivaji University, Kolhapur, Maharashtra, India.
Department of Biochemistry, The Institute of Science, Dr. Homi Bhabha State University, Mumbai, Maharashtra, India.
J Pharm Pharmacol. 2022 Jun 9;74(6):812-842. doi: 10.1093/jpp/rgab183.
Barleria, a large genus of the Acanthaceae family, comprises more than 300 species with diverse taxonomy, cytogenetics, phytochemistry and pharmacological potential. Therefore, the aim of this review is to critically assess the research on Barleria and provide guidance for future investigations.
The data were obtained from different sources, such as books, theses, journals and some of the websites and internet-based searches, published from 1901 to 2020. Data obtained from PubMed, Google Scholar, ScienceDirect, online electronic journals, SpringerLink, Wiley, etc. have also been used.
The species of this genus exhibit considerable medicinal properties. Cytogenetical data are scantily available with chromosome counts available for only 24 species. The most common chromosome number is 2n = 2x = 40. So far, 187 compounds are reported from Barleria species. The active principles, their uses, toxicity and pharmacological effects are discussed. Essential oils, flavones, flavonoids, glycosides, terpenes and terpenoids form the major compounds.
It is highly recommended that the pharmacological and economic potential of Barleria species should be exploited and more detailed studies and attention be geared towards its utilization and conservation. In addition, to ensure maximum pharmacological benefits and sustainable use, it is necessary to have empirical information explaining its ethnobotanical values as well as commercial potential.
爵床科的一个大属 Barleria 包含超过 300 种，具有多样化的分类学、细胞遗传学、植物化学和药理学潜力。因此，本综述的目的是批判性地评估 Barleria 的研究，并为未来的研究提供指导。
数据来自不同的来源，如书籍、论文、期刊以及一些网站和基于互联网的搜索，发表时间从 1901 年到 2020 年。还使用了来自 PubMed、Google Scholar、ScienceDirect、在线电子期刊、SpringerLink、Wiley 等的的数据。
该属的物种具有相当大的药用特性。细胞遗传学数据很少，仅有 24 个物种的染色体计数可用。最常见的染色体数是 2n = 2x = 40。迄今为止，已从 Barleria 种中报告了 187 种化合物。讨论了活性成分、用途、毒性和药理作用。精油、黄酮类、类黄酮、糖苷、萜类和类萜是主要化合物。
强烈建议开发 Barleria 物种的药理学和经济潜力，并对其利用和保护进行更详细的研究和关注。此外，为了确保最大的药理效益和可持续利用，有必要获得解释其民族植物学价值和商业潜力的经验信息。
