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对先天性心脏病患者的房性心动过速进行重复射频导管消融。

Repeat radiofrequency catheter ablation of atrial tachycardias in patients with congenital heart disease.

机构信息

Department of Pediatric Cardiology and Intensive Care Medicine, University Medical Center, Georg-August-University Göttingen, Göttingen, Germany.

出版信息

J Cardiovasc Electrophysiol. 2022 May;33(5):943-952. doi: 10.1111/jce.15422.

Abstract

INTRODUCTION

Atrial tachycardias (AT) in patients with congenital heart disease (CHD) are significantly contributing to morbidity and mortality. Aim of this study was to evaluate the long-term course of CHD patients requiring repeat ablation procedures (RAP) of AT.

PATIENTS AND METHODS

All 144 patients with CHD who had undergone ablation of AT at our center between January 2003 and October 2018 were enrolled. Patients were classified according to the complexity of CHD: complex CHD (cCHD), moderate CHD (mCHD), and simple CHD (sCHD).

RESULTS

A total of 101 RAP were performed in 64 patients. One RAP was performed in n = 40, two in n = 13, three in n = 10, and five in n = 1. Acute success rate was 82% (83/101) and was not associated with the complexity of CHD (p = 1.0). Number of procedures was lower in patients with sCHD than in patients with mCHD and cCHD (sCHD 1.3 ± 0.6, mCHD 1.8 ± 1.0, and cCHD 1.8 ± 1.1, p = .04). RAP were most frequent in patients after Fontan palliation or Atrial switch procedure (2.0 ± 1.1 [n = 41] vs. 1.6 ± 0.9 all others, p = .016) and in patients with multiple unstable AT's (2.5 ± 1.1 [n = 11] vs. 1.7 ± 1.0, p = .008). Major complications occurred in 4/101 procedures. Complete follow-up was available in 125 patients. Since last RAP 73% of the patients were in sinus/atrial rhythm and 34/125 patients (27%) with AT recurrence did not require re-ablation with mean follow-up of 52 ± 40 months.

CONCLUSIONS

Recurrences after ablation of AT in CHD patients were frequent. After RAP promising long-term results could be achieved. Data encourage repetitive ablation procedures in this patient population.

摘要

引言

在先天性心脏病(CHD)患者中,房性心动过速(AT)是导致发病率和死亡率升高的重要因素。本研究旨在评估需要重复消融治疗的 CHD 患者的长期病程。

患者和方法

2003 年 1 月至 2018 年 10 月期间,我们中心对 144 例 CHD 患者进行了 AT 消融术。根据 CHD 的复杂程度将患者进行分类:复杂 CHD(cCHD)、中度 CHD(mCHD)和简单 CHD(sCHD)。

结果

64 例患者共进行了 101 次重复消融术。40 例患者进行了 1 次重复消融术,13 例患者进行了 2 次,10 例患者进行了 3 次,1 例患者进行了 5 次。急性成功率为 82%(83/101),与 CHD 的复杂程度无关(p=1.0)。sCHD 患者的手术次数明显低于 mCHD 和 cCHD 患者(sCHD 1.3±0.6,mCHD 1.8±1.0,cCHD 1.8±1.1,p=0.04)。Fontan 姑息治疗或心房转换术后患者的重复消融术最为频繁(2.0±1.1[n=41] vs. 所有其他患者 1.6±0.9,p=0.016),多次出现不稳定 AT 的患者也更为频繁(2.5±1.1[n=11] vs. 1.7±1.0,p=0.008)。101 次重复消融术中,4 次发生重大并发症。125 例患者可获得完整的随访。最后一次重复消融术后,73%的患者为窦性/房性节律,34/125 例(27%)出现 AT 复发的患者无需再次消融,平均随访 52±40 个月。

结论

CHD 患者 AT 消融术后复发较为常见。重复消融术治疗可获得良好的长期效果。该数据支持对该患者群体进行重复消融治疗。

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