M Abdur Rahim Medical College, Dinajpur, Bangladesh.
Maharajgunj Medical Campus, Institute of Medicine, Maharajgunj, Kathmandu, Nepal.
JNMA J Nepal Med Assoc. 2021 Nov 19;59(242):1066-1068. doi: 10.31729/jnma.6472.
Sandifer syndrome is an extra oesophageal manifestation of gastrointestinal reflux disease that usually presents with torticollis and dystonia (often mimicking epilepsy). Here, we describe a case of a four and a half years old child with convulsion, neck contortion, and irritability. Gastrointestinal reflux disease was suspected on the earlier visit of the patient based on the presenting symptom of vomiting and cough. Electroencephalogram revealed normal findings. A barium meal radiograph was performed which was insignificant for gastrointestinal reflux disease and hiatal hernia. Complete blood count showed results suggestive of iron deficiency anaemia, while the rest of the biochemical parameters and the infection screening were normal. The case was confirmed by a medication trial for gastrointestinal reflux disease. This syndrome is often misdiagnosed as infantile seizure and musculoskeletal disorder. So, physicians need to have a sound knowledge of Sandifer Syndrome while assessing a child presenting with convulsion and torticollis.
桑迪弗综合征是胃食管反流病的一种食管外表现，常表现为斜颈和（或）肌肉张力障碍（常类似于癫痫）。本文描述了一例 4 岁半的儿童，表现为抽搐、颈部扭曲和易激惹。根据患者的呕吐和咳嗽症状，我们怀疑存在胃食管反流病。脑电图显示正常。进行钡餐检查，未见胃食管反流病和食管裂孔疝。全血细胞计数显示缺铁性贫血的结果，其余生化参数和感染筛查均正常。该病例通过胃肠道疾病药物治疗试验得到证实。该综合征常被误诊为婴儿癫痫和肌肉骨骼疾病。因此，在评估抽搐和斜颈的患儿时，医生需要对桑迪弗综合征有充分的了解。
