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三种不同消融技术行肺静脉隔离术后左房心动过速的发生率、电生理特征及消融结果

The Incidence, Electrophysiological Characteristics and Ablation Outcome of Left Atrial Tachycardias after Pulmonary Vein Isolation Using Three Different Ablation Technologies.

作者信息

Leitz Patrick, Wasmer Kristina, Andresen Christian, Güner Fatih, Köbe Julia, Rath Benjamin, Reinke Florian, Wolfes Julian, Lange Philipp S, Ellermann Christian, Frommeyer Gerrit, Eckardt Lars

机构信息

Department of Cardiology II-Electrophysiology, University Hospital Muenster, Cardiol, Albert-Schweitzer-Campus 1, Building A1, 48149 Muenster, Germany.

出版信息

J Cardiovasc Dev Dis. 2022 Feb 3;9(2):50. doi: 10.3390/jcdd9020050.

DOI:10.3390/jcdd9020050
PMID:35200703
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8879099/
Abstract

BACKGROUND

Left atrial tachycardias (LAT) are a well-known outcome of pulmonary vein isolation (PVI). Few data are available on whether the catheter used to perform PVI influences the incidence, as well as the characteristics of post PVI LAT. We present data on LAT following PVI by the following three ablation technologies: (1) phased multi-electrode radiofrequency catheter (PVAC), (2) irrigated single-tip catheter (iRF), and (3) cryoballoon ablation.

METHODS

Using a prospectively designed single-center database, we analyzed 650 patients (300 iRF, 150 PVAC, and 200 cryoballoon) with paroxysmal ( = 401) and persistent atrial fibrillation (AF), who underwent their first PVI at our center.

RESULTS

The three populations were comparable in their baseline characteristics; however, the cryoballoon group comprised a higher percentage of patients with persistent AF ( = 0.05). The LAT rates were 3.7% in the iRF group (mean follow-up 22 ± 14 months), 0.7% in the PVAC group (mean follow-up 21 ± 14 months), and 4% in the cryoballoon group (mean follow-up 15 ± 8 months). The predominant mechanism of LAT was macro-reentrant tachycardia. Reconnection of at least one pulmonary vein was observed in 87% of the patients who underwent 3D mapping. No predictors for LAT occurrence were identified.

CONCLUSION

The occurrence of LAT post PVI is rare; the predominant mechanism was macro-reentrant tachycardia. Reconnection of at least one pulmonary vein was observed in nearly all the LAT patients. In our retrospective analysis, the lowest rate of LAT was observed with the PVAC. No predictors for LAT occurrence were identified.

摘要

背景

左房性心动过速(LAT)是肺静脉隔离(PVI)的一个众所周知的结果。关于用于进行PVI的导管是否会影响PVI后LAT的发生率及其特征,目前可用的数据很少。我们展示了采用以下三种消融技术进行PVI后LAT的数据:(1)相控多电极射频导管(PVAC),(2)灌注单极导管(iRF),以及(3)冷冻球囊消融。

方法

利用前瞻性设计的单中心数据库,我们分析了650例阵发性(n = 401)和持续性房颤(AF)患者(300例iRF、150例PVAC和200例冷冻球囊),这些患者在我们中心接受了首次PVI。

结果

三组患者的基线特征具有可比性;然而,冷冻球囊组中持续性AF患者的比例更高(P = 0.05)。iRF组的LAT发生率为3.7%(平均随访22±14个月),PVAC组为0.7%(平均随访21±14个月),冷冻球囊组为4%(平均随访15±8个月)。LAT的主要机制是大折返性心动过速。在接受三维标测的患者中,87%观察到至少一条肺静脉重新连接。未发现LAT发生的预测因素。

结论

PVI后LAT的发生很罕见;主要机制是大折返性心动过速。几乎所有LAT患者均观察到至少一条肺静脉重新连接。在我们的回顾性分析中,PVAC的LAT发生率最低。未发现LAT发生的预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e523/8879099/9f1f37ffbfb0/jcdd-09-00050-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e523/8879099/e30ccae0abd3/jcdd-09-00050-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e523/8879099/9f1f37ffbfb0/jcdd-09-00050-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e523/8879099/e30ccae0abd3/jcdd-09-00050-g001a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e523/8879099/9f1f37ffbfb0/jcdd-09-00050-g002.jpg

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Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation.
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