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基于全介质非对称环形超表面的高灵敏度生物传感器。

Highly sensitive biosensor based on an all-dielectric asymmetric ring metasurface.

出版信息

Appl Opt. 2022 Feb 20;61(6):1349-1356. doi: 10.1364/AO.450739.

Abstract

We propose an all-dielectric asymmetric ring-cylindrical metasurface. Based on the analysis of transmission characteristics and the calculation of electromagnetic field distribution of the metasurface with this element structure, it is found that the high resonance of the ultra-narrowband can be realized when the symmetry of the ring-cylindrical structure is broken. Meanwhile, it is found that the degree of asymmetry of the ring, the refractive index of the material, the radius of the ring, and the substrate have great influence on the value and resonant frequency of the metasurface. Our proposed metasurface structure is applied to the detection of biological molecules based on the change in refractive index of biomolecular solutions. The designed metasurface with high sensitivity to detect biomolecules with different refractive indices, the value can reach 365.03, and the sensitivity is increased by 90.36 GHz/RIU compared to that without substrate, while the figure of merit value is as high as 100.56, providing label-free detection of biomolecules.

摘要

我们提出了一种全介质非对称环柱形超表面。基于对具有这种单元结构的超表面的传输特性的分析和电磁场分布的计算,发现当环柱形结构的对称性被破坏时,可以实现超窄带的高共振。同时,还发现环的不对称度、材料的折射率、环的半径和基底对超表面的共振频率和值有很大的影响。我们提出的超表面结构应用于基于生物分子溶液折射率变化的生物分子检测。设计的超表面具有高灵敏度,可以检测具有不同折射率的生物分子,值可达 365.03,与没有基底的相比,灵敏度提高了 90.36 GHz/RIU,而品质因数的值高达 100.56,实现了对生物分子的无标记检测。

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