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左心室辅助装置支持与纵向袖状胃切除术联合饮食用于心脏移植桥接。

Left Ventricular Assist Device Support and Longitudinal Sleeve Gastrectomy Combined With Diet in Bridge to Heart Transplant.

机构信息

Clinical Nutrition, Memorial Hermann-Texas Medical Center, Houston, Texas.

Department of Advanced Cardiopulmonary Therapies and Transplantation, Center for Advanced Heart Failure, University of Texas Health Science Center at Houston, Houston, Texas.

出版信息

Tex Heart Inst J. 2022 Jan 1;49(1). doi: 10.14503/THIJ-20-7521.

Abstract

Combining left ventricular assist device (LVAD) implantation and longitudinal sleeve gastrectomy may enable patients with morbid obesity to lose enough weight for heart transplant eligibility. In a retrospective study, we evaluated long-term outcomes of patients with body mass indexes ≥35 who underwent LVAD implantation and longitudinal sleeve gastrectomy during the same hospitalization (from January 2013 through July 2018) and then adhered to a dietary protocol. We included 22 patients (mean age, 49.9 ± 12.5 yr; mean preoperative body mass index, 43.3 ± 6.2). Eighteen months after gastrectomy, all 22 patients were alive, and 16 (73%) achieved a body mass index of less than 35. Myocardial recovery in 2 patients enabled LVAD removal. As of October 2020, 10 patients (45.5%) had undergone heart transplantation, 5 (22.3%) were waitlisted, 5 (22.3%) still had a body mass index ≥35, and 2 (9%) had died. With LVAD support, longitudinal sleeve gastrectomy, and dietary protocols, most of our patients with morbid obesity and advanced heart failure lost enough weight for transplant eligibility. Support from physicians and dietitians can maximize positive results in these patients.

摘要

将左心室辅助装置 (LVAD) 植入术和纵向袖状胃切除术相结合,可能使病态肥胖患者减轻足够的体重,以符合心脏移植的条件。在一项回顾性研究中,我们评估了在同一次住院期间(2013 年 1 月至 2018 年 7 月)接受 LVAD 植入术和纵向袖状胃切除术并随后遵循饮食方案的体重指数≥35 的患者的长期结果。我们纳入了 22 名患者(平均年龄 49.9 ± 12.5 岁;术前平均体重指数 43.3 ± 6.2)。胃切除术后 18 个月,所有 22 名患者均存活,16 名(73%)患者体重指数降至<35。2 名患者的心肌恢复后LVAD 被移除。截至 2020 年 10 月,10 名患者(45.5%)接受了心脏移植,5 名(22.3%)患者处于候补名单中,5 名(22.3%)患者体重指数仍≥35,2 名(9%)患者死亡。在 LVAD 支持、纵向袖状胃切除术和饮食方案的帮助下,我们的大多数病态肥胖和晚期心力衰竭患者减轻了足够的体重,以符合移植条件。医生和营养师的支持可以使这些患者获得最佳的结果。

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本文引用的文献

1
Laparoscopic sleeve gastrectomy in patients with heart failure and left ventricular assist devices as a bridge to transplant.
Surg Obes Relat Dis. 2018 Sep;14(9):1269-1273. doi: 10.1016/j.soard.2018.04.005. Epub 2018 Apr 19.
2
Sleeve Gastrectomy and Left Ventricular Assist Device for Heart Transplant.
JSLS. 2017 Jul-Sep;21(3). doi: 10.4293/JSLS.2017.00049.
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Laparoscopic sleeve gastrectomy in morbidly obese patients with end-stage heart failure and left ventricular assist device: medium-term results.
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