Díaz-Santana Pablo, Fernández Antonio, Díaz-Delgado Josue, Vela Ana Isabel, Domínguez Lucas, Suárez-Santana Cristian, Puig-Lozano Raquel, Fernández-Maldonado Carolina, Sierra Eva, Arbelo Manuel
Veterinary Histology and Pathology, Institute of Animal Health and Food Hygiene (IUSA), University of Las Palmas of Gran Canaria, 35413 Las Palmas de Gran Canaria, Spain.
TVMDL, Veterinary Medical Diagnostic Laboratory, Texas A&M University, Amarillo, TX 79016, USA.
Animals (Basel). 2022 Feb 11;12(4):434. doi: 10.3390/ani12040434.
We report the pathologic features of nocardiosis in five free-ranging delphinids from the Canary Islands and Andalusia, namely four striped dolphins () and one bottlenose dolphin (). All animals had a multiorgan (disseminated) pattern of infection involving suppurative to pyogranulomatous and thromboembolic lesions in two or more organs. Most affected organs were (by decreasing order) lung, pulmonary lymph nodes, liver, kidney, adrenal glands, and central nervous system. Typical intralesional and intravascular branched and filamentous bacteria were highlighted by Grocott's methenamine silver and Gram stains. Bacterial analysis including 16S rRNA gene sequencing identified in two striped dolphins and in one striped dolphin and the bottlenose dolphin. All dolphins tested ( = 4) for cetacean morbillivirus were negative; one dolphin had concurrent cutaneous herpesvirosis. These results provide the first record of in cetaceans, the first account of in free-ranging dolphins, and confirmation of nocardiosis in central eastern Atlantic Ocean. These results expand the known geographic range of nocardiosis in cetaceans.
我们报告了来自加那利群岛和安达卢西亚的5只野生海豚（4只条纹海豚和1只宽吻海豚）诺卡菌病的病理特征。所有动物均呈现多器官（播散性）感染模式，累及两个或更多器官的化脓性至脓性肉芽肿性病变和血栓栓塞性病变。受影响最严重的器官（按受累程度递减顺序）为肺、肺淋巴结、肝、肾、肾上腺和中枢神经系统。Grocott六胺银染色和革兰氏染色突出显示了典型的病灶内和血管内分支状及丝状细菌。包括16S rRNA基因测序在内的细菌分析在2只条纹海豚中鉴定出 ，在1只条纹海豚和宽吻海豚中鉴定出 。所有检测的海豚（n = 4）鲸类麻疹病毒检测均为阴性；1只海豚同时患有皮肤疱疹病毒病。这些结果提供了鲸类动物中 感染的首次记录、野生海豚中 感染的首次报道，以及中东大西洋诺卡菌病的确认。这些结果扩大了鲸类动物中诺卡菌病已知的地理范围。
