Al-Taani Ghaith M, Al-Azzam Sayer, Karasneh Reema A, Sadeq Adel Shaban, Mazrouei Nadia Al, Bond Stuart E, Conway Barbara R, Aldeyab Mamoon A
Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid 21163, Jordan.
Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid 22110, Jordan.
Antibiotics (Basel). 2022 Jan 28;11(2):175. doi: 10.3390/antibiotics11020175.
Antimicrobial resistance (AMR) is a serious healthcare problem that affects public health globally. Appropriate understanding and knowledge of prudent antimicrobial use and resistance, along with providing evidence-based information sources, are needed for informed antibiotic prescribing practices. This study aimed to assess the knowledge, opportunity, motivation, behavior of pharmacists and their information sources regarding antibiotic use and resistance in Jordan. An online cross-sectional questionnaire was developed and administered to pharmacists during the period of July-September 2021. The survey is an adapted version of the validated European Centre for Disease Prevention and Control (ECDC) survey for antibiotic use and resistance. Pharmacists from all sectors ( = 384), of whom 276 (71.9%) were community pharmacists, completed an online questionnaire. While respondents scored highly (>87%) on knowledge on effective use, unnecessary use, and associated side effects of antibiotics, lower scores were recorded for knowledge on the spread of antibiotic resistance (52.9%). Pharmacists support easy access to guidelines on managing infections in 56% of cases, and easy access to materials advising prudent antibiotic use and resistance in 39.8% of cases. One-third of respondents (37.0%) reported no knowledge of any initiatives on antibiotic awareness and resistance. Pharmacists were aware (13.3%), unaware (36.2%), or unsure (50.5%) of the existence of a national antibiotic resistance action plan. Pharmacists indicated an interest in receiving more information on resistance to antibiotics (55.2%), medical conditions for which antibiotics are used (53.1%), how to use antibiotics (45.1%), prescribing of antibiotics (34.4%), and links between the health of humans, animals, and the environment (28.6%). Findings can inform antimicrobial stewardship with required interventions to improve antibiotic use.
抗菌药物耐药性（AMR）是一个严重的医疗保健问题，在全球范围内影响着公众健康。要进行明智的抗生素处方实践，需要对抗菌药物的谨慎使用和耐药性有适当的理解和认识，并提供基于证据的信息来源。本研究旨在评估约旦药剂师关于抗生素使用和耐药性的知识、机会、动机、行为及其信息来源。2021年7月至9月期间，开发并向药剂师发放了一份在线横断面调查问卷。该调查是经过验证的欧洲疾病预防控制中心（ECDC）抗生素使用和耐药性调查的改编版本。来自各个部门的384名药剂师完成了在线问卷，其中276名（71.9%）是社区药剂师。虽然受访者在抗生素有效使用、不必要使用及相关副作用的知识方面得分较高（>87%），但在抗生素耐药性传播知识方面得分较低（52.9%）。56%的药剂师支持方便获取感染管理指南，39.8%的药剂师支持方便获取建议谨慎使用抗生素和耐药性的材料。三分之一的受访者（37.0%）表示不了解任何关于抗生素意识和耐药性的倡议。药剂师知晓（13.3%）、不知晓（36.2%）或不确定（50.5%）国家抗生素耐药性行动计划的存在。药剂师表示有兴趣获取更多关于抗生素耐药性（55.2%）、使用抗生素的医疗状况（53.1%）、如何使用抗生素（45.1%）、抗生素处方（34.4%）以及人类、动物和环境健康之间的联系（28.6%）的信息。研究结果可为抗菌药物管理提供参考，并通过必要的干预措施改善抗生素的使用。
