Herden Anna, Sabtan Deema, Warnecke Katja, Doll Christian, Furth Christian
Department of Nuclear Medicine, Chariteé-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.
Institute of Pathology, Chariteé-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Chariteéplatz 1, 10117 Berlin, Germany.
Diagnostics (Basel). 2022 Feb 2;12(2):389. doi: 10.3390/diagnostics12020389.
A 62-year-old-woman with a suspected Tumor-induced-osteomalacia (TIO), a rare neoplastic syndrome that results in renal phosphate wasting with hypophosphatemia, underwent Ga-DOTATOC PET/CT on the suspicion of a mesenchymal tumor producing Fibroblast growth factor 23 (FGF23). Imaging revealed a small osteolytic, somatostatin receptor (SSTR) positive lesion containing calcifications in the alveolar process of the maxilla. No other SSTR-positive focus was found. A biopsy was performed by an oral and maxillofacial surgeon that revealed a calcifying epithelial odontogenic tumor (Pindborg tumor). This case shows that epithelial odontogenic tumors as an uncommon benign tumor entity can also be SSTR-positive.
一名62岁女性疑似患有肿瘤诱导性骨软化症(TIO),这是一种罕见的肿瘤综合征,可导致肾性磷酸盐流失和低磷血症。因怀疑存在产生成纤维细胞生长因子23(FGF23)的间充质肿瘤,该患者接受了镓-奥曲肽PET/CT检查。影像学检查发现上颌牙槽突有一个小的溶骨性、生长抑素受体(SSTR)阳性病变,伴有钙化。未发现其他SSTR阳性病灶。口腔颌面外科医生进行了活检,结果显示为钙化上皮性牙源性肿瘤(平博肿瘤)。该病例表明,上皮性牙源性肿瘤作为一种罕见的良性肿瘤实体,也可为SSTR阳性。