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平博尔格瘤:特殊染色病理学

Pindborg tumor: Pathology with special stains.

作者信息

Gotmare Swati Shrikant, Pereira Treville, Shetty Subraj, Kesarkar Kashmira S

机构信息

Department of Oral and Maxillofacial Pathology and Microbiology, D Y Patil University School of Dentistry, Navi Mumbai, Maharashtra, India.

出版信息

Indian J Pathol Microbiol. 2018 Apr-Jun;61(2):239-241. doi: 10.4103/IJPM.IJPM_143_17.

Abstract

Odontogenic tumors constitute a wide spectrum of lesions ranging from malignant and benign neoplasms to dental hamartomas, all derived from the epithelial and ectomesenchymal remnants of the tooth forming apparatus. Calcifying epithelial odontogenic tumor (CEOT) is an uncommon, benign epithelial odontogenic tumor first described by Pindborg in 1956. It is a universally accepted eponym for this neoplasm. Pindborg tumor or CEOT is a locally aggressive neoplasm that accounts for 1% of the total odontogenic tumors, with recurrence in 14% of cases. The etiology of this tumor remains an enigma to the clinician. Pindborg suggested that the tumor arises from the remnants of reduced enamel epithelium of an unerupted tooth. Recent studies in literature report that the tumor arises from stratum intermedium. We report a case of Pindborg tumor in a 22-year-old male patient in the left mandibular posterior region. Radiographically, a well-defined radiolucency was associated with unerupted mandibular second molar which was displaced to the inferior border of the mandible. Along with routine haematoxylin and eosin stains, this case reports histopathological findings using Congo red stain and modified Gallegos stain.

摘要

牙源性肿瘤涵盖了广泛的病变,从恶性和良性肿瘤到牙错构瘤,所有这些都源自牙齿形成器官的上皮和外胚间叶残余组织。钙化上皮性牙源性肿瘤(CEOT)是一种罕见的良性上皮性牙源性肿瘤,于1956年由平德伯格首次描述。它是这种肿瘤被普遍接受的人名命名法。平德伯格瘤或CEOT是一种具有局部侵袭性的肿瘤,占牙源性肿瘤总数的1%,14%的病例会复发。该肿瘤的病因对临床医生来说仍是个谜。平德伯格认为该肿瘤起源于未萌出牙的釉质上皮残余组织。近期文献研究报告称该肿瘤起源于中间层。我们报告一例发生在一名22岁男性患者左下颌后部区域的平德伯格瘤。影像学上,一个边界清晰的透射区与未萌出的下颌第二磨牙相关,该磨牙向下移位至下颌下缘。除了常规苏木精和伊红染色外,本病例报告了使用刚果红染色和改良加列戈斯染色的组织病理学结果。

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