Lee Chan-Hyuk, Yi Sang Hak, Shin Byoung-Soo, Kang Hyun Goo
Department of Neurology, Jeonbuk National University Medical School and Hospital, Jeonju 54907, Korea.
Department of Neurology, Wonkwang University School of Medicine, Iksan 54538, Korea.
Diagnostics (Basel). 2022 Feb 3;12(2):398. doi: 10.3390/diagnostics12020398.
Atrial fibrillation and cerebral embolism are known to increase the risk of hemorrhagic transformation (HT). In addition, a sufficient number of collateral vessels in acute ischemic stroke can maintain the ischemic penumbra and prevent progression to the ischemic core, while an insufficient number of collateral vessels increase the HT risk after therapeutic recanalization. In this case, when the middle cerebral artery is recanalized, reperfusion injury may occur in the basal ganglia due to insufficient collateral vessels.
已知心房颤动和脑栓塞会增加出血性转化(HT)的风险。此外,急性缺血性卒中时足够数量的侧支血管可维持缺血半暗带并防止进展为缺血核心,而侧支血管数量不足会增加治疗性再通后发生HT的风险。在这种情况下,当中脑动脉再通时,由于侧支血管不足,基底节可能会发生再灌注损伤。