使用镓-PSMA和碘PET/US融合成像对PSMA阳性甲状腺结节进行多模态特征分析。
Multimodal Characterization of a PSMA-Positive Thyroid Nodule Using Ga-PSMA and Iodine PET/US Fusion Imaging.
作者信息
Freesmeyer Martin, Gühne Falk, Drescher Robert, Winkens Thomas, Gassler Nikolaus, Seifert Philipp
机构信息
Clinic of Nuclear Medicine, Jena University Hospital, 07749 Jena, Germany.
Section of Pathology, Institute of Forensic Medicine, Jena University Hospital, 07749 Jena, Germany.
出版信息
Diagnostics (Basel). 2022 Feb 12;12(2):472. doi: 10.3390/diagnostics12020472.
A 54-year-old male diagnosed with prostate cancer was referred for Gallium-PSMA-11 PET/CT. The scan revealed a solitary PSMA-positive thyroid lesion. On PET/ultrasound fusion imaging, a nodule with moderate risk of malignancy (TIRADS 4B) could be unambiguously correlated. Additional Iodine PET/ultrasound fusion imaging revealed normal iodine uptake within the PSMA-positive thyroid nodule. Fine-needle aspiration cytology was performed using an ultrasound needle-guidance system. The cytopathological investigation confirmed a benign thyroid nodule and excluded a thyroid carcinoma as well as a prostate cancer metastasis. Immunohistochemistry was positive for thyroglobulin staining.
一名54岁被诊断为前列腺癌的男性被转诊进行镓-PSMA-11 PET/CT检查。扫描显示一个孤立的PSMA阳性甲状腺病变。在PET/超声融合成像中，一个具有中度恶性风险的结节（甲状腺影像报告和数据系统4B类）可以明确关联。额外的碘PET/超声融合成像显示PSMA阳性甲状腺结节内碘摄取正常。使用超声针引导系统进行了细针穿刺细胞学检查。细胞病理学检查证实为良性甲状腺结节，排除了甲状腺癌以及前列腺癌转移。免疫组织化学甲状腺球蛋白染色呈阳性。
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