Di Marco Roberto, Pistonesi Francesca, Cianci Valeria, Biundo Roberta, Weis Luca, Tognolo Lucrezia, Baba Alfonc, Rubega Maria, Gentile Giovanni, Tedesco Chiara, Carecchio Miryam, Antonini Angelo, Masiero Stefano
Parkinson and Movement Disorders Unit, Study Centre on Neurodegeneration (CESNE), Department of Neuroscience, University of Padova, Via Giustiniani 5, 35128 Padova, Italy.
Department of Neuroscience, School of Physical Medicine and Rehabilitation, University of Padova, Via Giustiniani 2, 35128 Padova, Italy.
Healthcare (Basel). 2022 Feb 14;10(2):368. doi: 10.3390/healthcare10020368.
The main objective of this study is to test the effect of thermal aquatic exercise on motor symptoms and quality of life in people with Parkinson's Disease (PD). Fourteen participants with diagnosis of idiopathic PD completed the whole rehabilitation session and evaluation protocol (Hoehn and Yahr in OFF state: 2-3; Mini Mental State Examination >24; stable pharmacological treatment in the 3 months prior participating in the study). Cognitive and motor status, functional abilities and quality of life were assessed at baseline and after an intensive rehabilitation program in thermal water (12 sessions of 45 min in a 1.4 m depth pool at 32-36 ∘C). The Mini Balance Evaluation System Test (Mini-BESTest) and the PD Quality of Life Questionnaire (PDQ-39) were considered as main outcomes. Secondary assessment measures evaluated motor symptoms and quality of life and psychological well-being. Participants kept good cognitive and functional status after treatment. Balance of all the participants significantly improved (Mini-BESTest: p<0.01). The PDQ-39 significantly improved after rehabilitation (p=0.038), with significance being driven by dimensions strongly related to motor status. Thermal aquatic exercise may represent a promising rehabilitation tool to prevent the impact of motor symptoms on daily-life activities of people with PD. PDQ-39 improvement foreshows good effects of the intervention on quality of life and psychological well-being.
本研究的主要目的是测试热水平运动对帕金森病(PD)患者运动症状和生活质量的影响。14名被诊断为特发性帕金森病的参与者完成了整个康复疗程和评估方案(处于“关”状态时的Hoehn和Yahr分级:2 - 3级;简易精神状态检查表得分>24分;在参与研究前3个月内药物治疗稳定)。在基线时以及在热水中进行强化康复计划后(在1.4米深、水温32 - 36摄氏度的水池中进行12次每次45分钟的训练),对认知和运动状态、功能能力以及生活质量进行了评估。迷你平衡评估系统测试(Mini - BESTest)和帕金森病生活质量问卷(PDQ - 39)被视为主要结果指标。次要评估指标评估了运动症状、生活质量和心理健康状况。治疗后参与者保持了良好的认知和功能状态。所有参与者的平衡能力显著改善(Mini - BESTest:p<0.01)。康复后PDQ - 39显著改善(p = 0.038),改善主要由与运动状态密切相关的维度驱动。热水平运动可能是一种有前景的康复工具,可防止运动症状对帕金森病患者日常生活活动产生影响。PDQ - 39的改善预示着该干预措施对生活质量和心理健康状况有良好效果。