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乳腺癌全乳切除术后单纯脂肪填充乳房重建:技术描述及生活质量评估

Breast Reconstruction by Exclusive Lipofilling after Total Mastectomy for Breast Cancer: Description of the Technique and Evaluation of Quality of Life.

作者信息

Piffer Alexandre, Aubry Gabrielle, Cannistra Claudio, Popescu Nathalie, Nikpayam Maryam, Koskas Martin, Uzan Catherine, Bichet Jean-Christophe, Canlorbe Geoffroy

机构信息

Department of Gynecological and Breast Surgery and Oncology, Assistance Publique des Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière University Hospital, 75013 Paris, France.

Department of Gynecology, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Bichat, 75018 Paris, France.

出版信息

J Pers Med. 2022 Jan 25;12(2):153. doi: 10.3390/jpm12020153.

DOI:10.3390/jpm12020153
PMID:35207642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8876120/
Abstract

BACKGROUND

The objective of this work was to describe the technique of exclusive lipofilling in breast reconstruction after total mastectomy, to evaluate the satisfaction and quality of life of the patients, and to explore current literature on the subject.

METHODS

We conducted a retrospective observational multicentric study from January 2013 to April 2020. The modalities of surgery, esthetic result, and patient satisfaction were evaluated with the breast reconstruction module of BREAST-Q.

RESULTS

Complete data were available for 37 patients. The mean number of sessions was 2.2 (standard deviation 1.1), spread over an average of 6.8 months (SD 6.9). The average total volume of fat transferred was 566.4 mL. The complication rate was 18.9%. No severe complication was observed (Clavien-Dindo 3/4). Two patients were diagnosed with recurrence, in a metastatic mode (5.4%). The average satisfaction rate was 68.4% (SD 24.8) for psychosocial well-being and 64.5% (SD 24.1) for sexual well-being. The satisfaction rate was 60.2% (SD 20.9) for the image of the reconstructed breast and 82.7% (SD 21.9) for locoregional comfort.

CONCLUSIONS

Breast reconstruction by exclusive lipofilling after total mastectomy provides satisfactory quality of life scores. The simplicity of the surgical technique and equipment required, and the high satisfaction rate confirm that lipofilling should be included in the panel of choice of breast reconstruction techniques.

摘要

背景

本研究旨在描述全乳切除术后单纯脂肪填充乳房重建技术,评估患者的满意度和生活质量,并探讨该主题的现有文献。

方法

我们进行了一项回顾性观察性多中心研究,时间跨度为2013年1月至2020年4月。采用BREAST-Q乳房重建模块评估手术方式、美学效果和患者满意度。

结果

37例患者有完整数据。平均手术次数为2.2次(标准差1.1),平均历时6.8个月(标准差6.9)。平均脂肪移植总量为566.4 mL。并发症发生率为18.9%。未观察到严重并发症(Clavien-Dindo 3/4级)。2例患者被诊断为转移复发(5.4%)。心理社会幸福感的平均满意率为68.4%(标准差24.8),性幸福感的平均满意率为64.5%(标准差24.1)。重建乳房外观的满意率为60.2%(标准差20.9),局部区域舒适度的满意率为82.7%(标准差21.9)。

结论

全乳切除术后单纯脂肪填充乳房重建可提供令人满意的生活质量评分。手术技术和所需设备的简单性以及高满意率证实,脂肪填充应纳入乳房重建技术的选择范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/60aa9542a500/jpm-12-00153-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/2574b37bd5b8/jpm-12-00153-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/a066117a23d2/jpm-12-00153-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/ff594ac3d2a1/jpm-12-00153-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/60aa9542a500/jpm-12-00153-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/2574b37bd5b8/jpm-12-00153-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/a066117a23d2/jpm-12-00153-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/ff594ac3d2a1/jpm-12-00153-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c15d/8876120/60aa9542a500/jpm-12-00153-g004.jpg

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The Influence of Fat Grafting on Breast Imaging after Postmastectomy Reconstruction: A Matched Cohort Analysis.脂肪移植对乳腺癌根治术后乳房重建影像学的影响:一项匹配队列分析。
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