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智能手机进行血流动力学监测——一项比较性前瞻性观察研究的初步报告

Hemodynamic Monitoring by Smartphone-Preliminary Report from a Comparative Prospective Observational Study.

作者信息

Pluta Michał P, Dziech Magdalena, Zachura Mateusz N, Szczepańska Anna J, Czempik Piotr F, Liberski Piotr S, Krzych Łukasz J

机构信息

Department of Anaesthesiology and Intensive Care, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medyków 14 Street, 40752 Katowice, Poland.

Emergency Medicine Department, St. Barbara's Memorial Hospital No. 5 Trauma Center, Medyków 1 Square, 41200 Sosnowiec, Poland.

出版信息

J Pers Med. 2022 Feb 1;12(2):200. doi: 10.3390/jpm12020200.

Abstract

BACKGROUND

Advanced hemodynamic monitoring supports making therapeutic decisions in critically ill patients. New technologies, including mobile health, have been introduced into the hemodynamic monitoring armamentarium. However, each monitoring method has potential limitations-content, technical and organizational. The aim of this study was to assess the comparability between measurements obtained with two arterial pressure cardiac output methods: Capstesia™ smartphone hemodynamic software (CS) and LiDCO Rapid™ uncalibrated hemodynamic monitor (LR).

METHODS

The initial analysis included 16 patients in the period 06-09 2020 without limitations that could make the results obtained unreliable. Eighty pairs of cardiac output measurements were obtained. The comparability of cardiac output results obtained with both methods was assessed using the Spearman's rank correlation coefficient (R), the intra-class correlation (CCC) and the Bland-Altman curves analysis (B-A).

RESULTS

The median (IQR) cardiac output measured with CS and LR were 4.6 (3.9-5.7) and 5.5 (4.6-7.4) L min, respectively. In the B-A analysis, CS cardiac output values were on average 1.2 (95% CI -2.1-4.4) L min lower than LR values. The correlation between cardiac output with CS and LR was moderate ( = 0.5; = 0.04). After adjusting for the presence of the dicrotic notch on the pulse waveform, in the group of eight patients with a visible dicrotic notch, the CS and LR results differed by only 0.1 (95% CI -0.8-1.1) L min, the correlation between CS and LR was close to complete ( = 0.96; < 0.001), and the percentage error was 40%, with a CCC-CS of 0.98 (95% CI 0.95-0.99).

CONCLUSIONS

The Capstesia smartphone software can provide an alternative method of cardiac output assessment in patients meeting arterial pressure cardiac output evaluation criteria with a clearly discernible dicrotic notch on the arterial pulse pressure waveform. It is necessary to confirm the obtained observations on a larger group of patients; however, it may potentially make objective hemodynamic measurements ubiquitous in patients with invasive arterial pressure monitoring with a clearly discernible dicrotic notch.

摘要

背景

先进的血流动力学监测有助于为重症患者做出治疗决策。包括移动健康技术在内的新技术已被引入血流动力学监测手段中。然而,每种监测方法都有潜在的局限性,包括内容、技术和组织方面。本研究的目的是评估两种动脉压心输出量测量方法的测量结果之间的可比性:Capstesia™智能手机血流动力学软件(CS)和LiDCO Rapid™未校准血流动力学监测仪(LR)。

方法

初始分析纳入了2020年6月至9月期间的16例患者,这些患者不存在可能使所获结果不可靠的限制因素。共获得80对心输出量测量值。使用Spearman等级相关系数(R)、组内相关系数(CCC)和Bland-Altman曲线分析(B-A)评估两种方法所获心输出量结果的可比性。

结果

用CS和LR测量的心输出量中位数(四分位间距)分别为4.6(3.9 - 5.7)L/min和5.5(4.6 - 7.4)L/min。在B-A分析中,CS测量的心输出量值平均比LR值低1.2(95%可信区间 -2.1 - 4.4)L/min。CS和LR的心输出量之间的相关性为中等(R = 0.5;P = 0.04)。在对脉搏波形上重搏波切迹的存在进行校正后,在8例有明显重搏波切迹的患者组中,CS和LR的结果仅相差0.1(95%可信区间 -0.8 - 1.1)L/min,CS和LR之间的相关性接近完全相关(R = 0.96;P < 0.001),百分比误差为40%,CS的CCC为0.98(95%可信区间0.95 - 0.99)。

结论

对于符合动脉压心输出量评估标准且动脉脉压波形上有清晰可辨重搏波切迹的患者,Capstesia智能手机软件可提供一种替代的心输出量评估方法。有必要在更大规模的患者群体中证实所获观察结果;然而,它可能会使有创动脉压监测且有清晰可辨重搏波切迹的患者能够普遍进行客观的血流动力学测量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63c9/8876504/272795236b6d/jpm-12-00200-g001.jpg

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