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严重骨质疏松性骨折患者后路脊柱全长切除术后的结果——来自两个中心的回顾性分析。

Outcome after Posterior Vertebral Column Resection in Patients with Severe Osteoporotic Fractures-A Retrospective Analysis from Two Centers.

机构信息

Division of Spine Surgery, Department of Trauma and Orthopedic Surgery, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.

Clinic for Trauma, Orthopedics and Plastic Surgery, University Medical Center Göttingen, Georg-August-Universität, 37075 Göttingen, Germany.

出版信息

Medicina (Kaunas). 2022 Feb 12;58(2):277. doi: 10.3390/medicina58020277.

Abstract

In osteoporotic fractures of the spine with resulting kyphosis and threatening compression of neural structures, therapeutic decisions are difficult. The posterior vertebral column resection (pVCR) has been described by different authors as a surgical treatment in a single-stage posterior procedure. The aim of this study is to evaluate midterm outcomes of patients treated by pVCR due to severe osteoporotic fractures. Retrospective data analysis of all the patients treated for osteoporotic fractures by pVCR from 2012-2020 at two centers was performed. Demographic data, visual analog scale (VAS), Frankel scale (FS), Karnofsky performance status (KPS), radiological result and spinal fusion rates were evaluated. A total of 17 patients were included. The mean age was 70 ± 10.2 y. The mean VAS decreased significantly from 7.7 ± 2.8 preoperatively to 3.0 ± 1.6 at last follow-up ( < 0.001) and the segmental kyphosis decreased from 29.4 ± 14.1° to 7.9 ± 8.0° ( < 0.001). The neurologic function on the FS did not worsen in any and improved in four of the patients. The median KPS remained stable over the whole observation period (70% vs. 70%). Spinal fusion was observed in nine out of nine patients who received CT follow-up >120 days after index surgery. This study showed that pVCR is a safe surgical technique with few surgical complications and no neurological deterioration considering the cohort. The patients' segmental kyphosis and VAS improved significantly, while the KPS remained stable.

摘要

在伴有后凸畸形和神经结构受压危险的骨质疏松性脊柱骨折中,治疗决策较为困难。后路全脊椎切除(pVCR)已被不同作者描述为一种在单一后路手术中进行的治疗方法。本研究旨在评估因严重骨质疏松性骨折而接受 pVCR 治疗的患者的中期结果。

对 2012 年至 2020 年在两个中心因骨质疏松性骨折接受 pVCR 治疗的所有患者进行回顾性数据分析。评估了人口统计学数据、视觉模拟量表(VAS)、Frankel 量表(FS)、Karnofsky 表现状态(KPS)、影像学结果和脊柱融合率。

共纳入 17 例患者。平均年龄为 70 ± 10.2 岁。VAS 平均值从术前的 7.7 ± 2.8 显著降低至末次随访时的 3.0 ± 1.6(<0.001),节段后凸角从 29.4 ± 14.1°降低至 7.9 ± 8.0°(<0.001)。FS 的神经功能在任何患者中均未恶化,在 4 例患者中得到改善。整个观察期间,KPS 中位数保持稳定(70% vs. 70%)。9 例接受 CT 随访>120 天的患者中有 9 例观察到脊柱融合。

本研究表明,pVCR 是一种安全的手术技术,手术并发症少,且考虑到本队列,神经功能无恶化。患者的节段后凸和 VAS 显著改善,而 KPS 保持稳定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6894/8879154/2d4a6ab0071b/medicina-58-00277-g001.jpg

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