（Benth.）Prance 的植物化学特性。

Phytochemical Characterizations of (Benth.) Prance.

机构信息

H. E. J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan.

Sino-Pakistan Cooperation Center for Traditional Chinese Medicine, Hunan University of Medicine, Huaihua 418000, China.

出版信息

Molecules. 2022 Feb 15;27(4):1316. doi: 10.3390/molecules27041316.

DOI:10.3390/molecules27041316

PMID:35209101

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8879441/

Abstract

Two new ursane-type triterpenoids, named Polyanside A () and B (), along with eleven known compounds (-), were isolated and elucidated from (Benth.) Prance. The structures of these compounds were elucidated based on chemical evidence and multiple spectroscopic data. Isolated compounds were evaluated for anti-cancer, anti-inflammatory activities, and cytotoxicity on a normal human cell line (BJ). None of them showed activity and cytotoxicity. The hexane fraction was analyzed by GC-MS, resulting in the identification of forty-one compounds. This is the first comprehensive study on the phytochemistry of .

摘要

从（Benth.）Prance 中分离得到了两种新的五环三萜类化合物，命名为 Polyanside A()和 B()，以及十一种已知化合物(-)。这些化合物的结构是根据化学证据和多种光谱数据阐明的。对分离得到的化合物进行了抗癌、抗炎活性以及对正常人体细胞系（BJ）的细胞毒性评价，结果表明它们均无活性和细胞毒性。通过 GC-MS 对正己烷馏分进行分析，共鉴定出 41 种化合物。这是对 Polyanside 属植物化学成分的首次全面研究。