Cohen Susan, Flibotte John
Department of Pediatrics, Division of Neonatology, Medical College of Wisconsin, 999 North 92nd Street, CCC 410, Milwaukee, WI 53226, USA.
Department of Pediatrics, Division of Neonatology, Children's Hospital of Phildealphia & the Perelman School of Medicine at the University of Pennsylvania, 34th & Civic Center Boulevard, Philadelphia, PA 19104, USA.
Clin Perinatol. 2022 Mar;49(1):15-25. doi: 10.1016/j.clp.2021.11.002. Epub 2022 Jan 21.
The incidence of intraventricular hemorrhage (IVH) has overall declined to 15% to 20% of preterm infants with birth weight less than 1500 g. One of the major complications of severe IVH is posthemorrhagic ventricular dilation (PHVD). Nearly 10% of all infants with IVH and 20% of infants with severe IVH will develop progressive PHVD requiring surgical intervention to prevent parenchymal damage in the developing brain. This review focuses on the controversies regarding posthemorrhagic hydrocephalus interventions with a focus on how to interpret recent data from trials that some have seen as heralding a call toward more aggressive intervention.
脑室内出血（IVH）的发生率总体上已降至出生体重低于1500克的早产儿的15%至20%。严重IVH的主要并发症之一是出血后脑室扩张（PHVD）。所有IVH患儿中有近10%，严重IVH患儿中有20%会发展为进行性PHVD，需要手术干预以防止发育中的大脑实质受损。本综述重点关注出血后脑积水干预措施的争议，重点在于如何解读一些人认为预示着需要更积极干预的试验的最新数据。
