Markman M
West J Med. 1986 May;144(5):580-5.
The development of a clinically apparent paraneoplastic syndrome in a patient with malignant disease is cause for considerable concern as the symptoms can be as serious and difficult to deal with as those produced by the cancer itself. While the information in the medical literature concerning the response of paraneoplastic processes to specific antineoplastic therapy is limited, case reports and small series would suggest that a number of syndromes are alleviated with successful treatment of the underlying neoplasm. As treatment programs for advanced malignant disease improve, a larger percentage of patients suffering from the effects of paraneoplastic processes will benefit from therapy directed at their cancer.
恶性疾病患者出现临床上明显的副肿瘤综合征令人相当担忧，因为这些症状可能与癌症本身所产生的症状一样严重且难以处理。虽然医学文献中关于副肿瘤过程对特定抗肿瘤治疗反应的信息有限，但病例报告和小系列研究表明，随着潜在肿瘤的成功治疗，一些综合征会得到缓解。随着晚期恶性疾病治疗方案的改善，更多受副肿瘤过程影响的患者将从针对其癌症的治疗中受益。
