A review of the literature on previous cases of drug-induced pemphigus as well as two case reports of pyritinole-induced pemphigus show a few characteristics: D-penicillamine was responsible in 42 cases, pyritinole in 4 cases, the two case reports included. Superficial pemphigus was seen in about 75% of the cases, most times associated with preexistent autoimmunological disorders. Immunological findings were identical with normal, non-drug-induced pemphigus, while the prognosis was better under mostly necessary immunosuppressive therapy at relatively low doses.
42例由D-青霉胺引起，4例由吡硫醇引起，包括这两例病例报告。约75%的病例为浅表性天疱疮，大多数情况下与先前存在的自身免疫性疾病有关。免疫学检查结果与正常的、非药物诱发的天疱疮相同，而在大多必要的相对低剂量免疫抑制治疗下预后较好。
