[Report on two cases of bullous manifestations, one of which being a pemphigus, induced by penicillamine (author's transl)].

Cutaneous bullous disease may be induced by D-penicillamin. We have briefly reviewed what was then possible: bullosa epidermolysis, pemphigus, bullous toxiderma. We have had the opportunity to observe twice this phenomenon. In one case, as already mentioned about fifteen times in the literature, it was a pemphigus. Its clinical, histological and immunological features are mentioned, and its good prognosis confirmed. The other case gives matter to discussion about toxic pre-pemphigus.