Department of Orthopaedics and Traumatology, Acibadem Kadikoy Hospital, Istanbul, Turkey. Email:
Department of Cardiovascular Surgery, Sultan Abdulhamid Han Teaching and Research Hospital, Istanbul, Turkey.
Cardiovasc J Afr. 2022;33(6):313-316. doi: 10.5830/CVJA-2022-012. Epub 2022 Feb 23.
Critical limb ischaemia (CLI) is the most severe state of peripheral arterial disease and is one of the major causes of lower-limb amputations. One of the treatment choices is prosthetic vascular grafts. Despite treatment, CLI may lead to amputation owing to infection or progressive ischaemia. The aim of this study was to show that multidisciplinary planning and surgery for CLI patients with prosthetic grafts decreased the duration of hospital stay, costs, risk of infection and ascending conversion of the amputation level.
Forty-two above-knee amputation patients with grafts were retrospectively evaluated. Group A patients ( = 24) had partial excision and group B patients ( = 18) total excision with or without saphenous patch-plasty, according to the patency of the deep femoral artery. Growth in wound culture, antibiotic therapy duration, conversion to hip disarticulation and hospitalisation periods were compared.
Differences in growth of wound culture ( = 0.007), antibiotic duration ( = 0.003), hip disarticulation ( = 0.029) and duration of hospital stay ( = 0.0001) between the two groups were found to be statistically significant ( < 0.05).
Management of CLI patients is a complex process, and a multidisciplinary approach is key to avoiding undesirable outcomes. Meticulous planning, including excision of the total graft, while ensuring the vascular supply, is essential.
严重肢体缺血(CLI)是外周动脉疾病最严重的状态,也是下肢截肢的主要原因之一。治疗选择之一是假体血管移植物。尽管进行了治疗,但 CLI 可能会因感染或进行性缺血而导致截肢。本研究旨在表明,对 CLI 患者进行假体移植物的多学科规划和手术可以缩短住院时间、降低成本、降低感染风险和减少截肢水平的上升转换。
回顾性评估了 42 例接受假体移植的膝上截肢患者。根据股深动脉的通畅性,A 组患者(n=24)行部分切除术,B 组患者(n=18)行全切除术,伴或不伴大隐静脉补片成形术。比较两组患者的伤口培养物生长情况、抗生素治疗时间、髋关节离断转换率和住院时间。
两组患者的伤口培养物生长( = 0.007)、抗生素使用时间( = 0.003)、髋关节离断( = 0.029)和住院时间( = 0.0001)差异均有统计学意义( < 0.05)。
CLI 患者的管理是一个复杂的过程,多学科方法是避免不良结果的关键。细致的规划,包括切除整个移植物,同时确保血管供应,是至关重要的。