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本文引用的文献

1
Living with Amputation: Anxiety and Depression Correlates.与截肢共存:焦虑和抑郁的相关因素。
J Clin Diagn Res. 2016 Sep;10(9):RC09-RC12. doi: 10.7860/JCDR/2016/20316.8417. Epub 2016 Sep 1.
2
Management of Critical Limb Ischemia.严重肢体缺血的管理
Circ Cardiovasc Interv. 2016 Feb;9(2):e001946. doi: 10.1161/CIRCINTERVENTIONS.115.001946.
3
Remnant prosthetic graft in revision or limb-salvage surgery: routine complete excision?翻修或保肢手术中残留的人工血管移植物:常规完全切除?
Ann Vasc Surg. 2014 Aug;28(6):1566.e11-5. doi: 10.1016/j.avsg.2013.12.034. Epub 2014 Feb 8.
4
Epidemiology of limb loss.肢体缺失的流行病学。
Phys Med Rehabil Clin N Am. 2014 Feb;25(1):1-8. doi: 10.1016/j.pmr.2013.09.001.
5
Vascular graft infections.血管移植物感染。
Swiss Med Wkly. 2013 Jan 24;143:w13754. doi: 10.4414/smw.2013.13754. eCollection 2013.
6
Critical limb ischaemia: initial treatment and predictors of amputation-free survival.严重肢体缺血:初始治疗和免于截肢的生存预测因素。
Eur J Vasc Endovasc Surg. 2012 Jan;43(1):55-61. doi: 10.1016/j.ejvs.2011.09.010. Epub 2011 Oct 15.
7
Conservative treatment of vascular prosthetic graft infection is associated with high mortality.血管人工移植物感染的保守治疗与高死亡率相关。
Am J Surg. 2010 Jul;200(1):47-52. doi: 10.1016/j.amjsurg.2009.05.018. Epub 2010 Jan 15.
8
Reamputation, mortality, and health care costs among persons with dysvascular lower-limb amputations.血管性下肢截肢患者的再次截肢、死亡率和医疗保健成本。
Arch Phys Med Rehabil. 2005 Mar;86(3):480-6. doi: 10.1016/j.apmr.2004.06.072.
9
Management of failed prosthetic grafts at the time of major lower extremity amputation.下肢大截肢时人工血管移植失败的处理
J Vasc Surg. 1988 May;7(5):673-6.
10
Energy expenditure during walking in subjects with tibial rotationplasty, above-knee amputation, or hip disarticulation.胫骨旋转成形术、大腿截肢或髋关节离断术患者行走时的能量消耗。
Arch Phys Med Rehabil. 1992 Dec;73(12):1174-80.

膝上截肢的人造血管移植物管理。

Prosthetic vascular graft management in above-knee amputations.

机构信息

Department of Orthopaedics and Traumatology, Acibadem Kadikoy Hospital, Istanbul, Turkey. Email:

Department of Cardiovascular Surgery, Sultan Abdulhamid Han Teaching and Research Hospital, Istanbul, Turkey.

出版信息

Cardiovasc J Afr. 2022;33(6):313-316. doi: 10.5830/CVJA-2022-012. Epub 2022 Feb 23.

DOI:10.5830/CVJA-2022-012
PMID:35211716
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10031853/
Abstract

OBJECTIVE

Critical limb ischaemia (CLI) is the most severe state of peripheral arterial disease and is one of the major causes of lower-limb amputations. One of the treatment choices is prosthetic vascular grafts. Despite treatment, CLI may lead to amputation owing to infection or progressive ischaemia. The aim of this study was to show that multidisciplinary planning and surgery for CLI patients with prosthetic grafts decreased the duration of hospital stay, costs, risk of infection and ascending conversion of the amputation level.

METHODS

Forty-two above-knee amputation patients with grafts were retrospectively evaluated. Group A patients ( = 24) had partial excision and group B patients ( = 18) total excision with or without saphenous patch-plasty, according to the patency of the deep femoral artery. Growth in wound culture, antibiotic therapy duration, conversion to hip disarticulation and hospitalisation periods were compared.

RESULTS

Differences in growth of wound culture ( = 0.007), antibiotic duration ( = 0.003), hip disarticulation ( = 0.029) and duration of hospital stay ( = 0.0001) between the two groups were found to be statistically significant ( < 0.05).

CONCLUSIONS

Management of CLI patients is a complex process, and a multidisciplinary approach is key to avoiding undesirable outcomes. Meticulous planning, including excision of the total graft, while ensuring the vascular supply, is essential.

摘要

目的

严重肢体缺血(CLI)是外周动脉疾病最严重的状态,也是下肢截肢的主要原因之一。治疗选择之一是假体血管移植物。尽管进行了治疗,但 CLI 可能会因感染或进行性缺血而导致截肢。本研究旨在表明,对 CLI 患者进行假体移植物的多学科规划和手术可以缩短住院时间、降低成本、降低感染风险和减少截肢水平的上升转换。

方法

回顾性评估了 42 例接受假体移植的膝上截肢患者。根据股深动脉的通畅性,A 组患者(n=24)行部分切除术,B 组患者(n=18)行全切除术,伴或不伴大隐静脉补片成形术。比较两组患者的伤口培养物生长情况、抗生素治疗时间、髋关节离断转换率和住院时间。

结果

两组患者的伤口培养物生长( = 0.007)、抗生素使用时间( = 0.003)、髋关节离断( = 0.029)和住院时间( = 0.0001)差异均有统计学意义( < 0.05)。

结论

CLI 患者的管理是一个复杂的过程,多学科方法是避免不良结果的关键。细致的规划,包括切除整个移植物,同时确保血管供应,是至关重要的。