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Basophil CD63 assay to peanut allergens accurately diagnoses peanut allergy in patient with negative skin prick test and very low specific IgE.

作者信息

Marrs Tom, Brough Helen A, Kwok Matthew, Lack Gideon, Santos Alexandra F

机构信息

Children's Allergy Service, Evelina London, Guy's and St Thomas' Hospital NHS Foundation Trust, London, UK.

Department of Women and Children's Health (Paediatric Allergy), School of Population Health and Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.

出版信息

Pediatr Allergy Immunol. 2022 Feb;33(2):e13739. doi: 10.1111/pai.13739.

DOI:10.1111/pai.13739
PMID:35212037
Abstract
摘要

相似文献

1
Basophil CD63 assay to peanut allergens accurately diagnoses peanut allergy in patient with negative skin prick test and very low specific IgE.嗜碱性粒细胞CD63检测花生过敏原可准确诊断皮肤点刺试验阴性且特异性IgE水平极低的患者是否对花生过敏。
Pediatr Allergy Immunol. 2022 Feb;33(2):e13739. doi: 10.1111/pai.13739.
2
Early decrease in basophil sensitivity to Ara h 2 precedes sustained unresponsiveness after peanut oral immunotherapy.花生口服免疫治疗后，嗜碱性粒细胞对 Ara h 2 的敏感性早期下降先于持续无反应。
J Allergy Clin Immunol. 2019 Nov;144(5):1310-1319.e4. doi: 10.1016/j.jaci.2019.07.028. Epub 2019 Aug 1.
3
Modified oral food challenge used with sensitization biomarkers provides more real-life clinical thresholds for peanut allergy.改良的口服食物激发试验结合致敏生物标志物，为花生过敏提供了更符合实际临床情况的阈值。
J Allergy Clin Immunol. 2014 Aug;134(2):390-8. doi: 10.1016/j.jaci.2014.03.035. Epub 2014 May 13.
4
Basophil allergen threshold sensitivity, CD-sens, IgE-sensitization and DBPCFC in peanut-sensitized children.花生致敏儿童的嗜碱性粒细胞变应原阈敏感性、CD-sens、IgE 致敏和 DBPCFC。
Allergy. 2012 Feb;67(2):242-7. doi: 10.1111/j.1398-9995.2011.02754.x. Epub 2011 Nov 30.
5
Distinct parameters of the basophil activation test reflect the severity and threshold of allergic reactions to peanut.嗜碱性粒细胞活化试验的不同参数反映了对花生过敏反应的严重程度和阈值。
J Allergy Clin Immunol. 2015 Jan;135(1):179-86. doi: 10.1016/j.jaci.2014.09.001.
6
Relevance of Ara h1, Ara h2 and Ara h3 in peanut-allergic patients, as determined by immunoglobulin E Western blotting, basophil-histamine release and intracutaneous testing: Ara h2 is the most important peanut allergen.通过免疫球蛋白E免疫印迹法、嗜碱性粒细胞组胺释放试验和皮内试验测定Ara h1、Ara h2和Ara h3在花生过敏患者中的相关性：Ara h2是最重要的花生过敏原。
Clin Exp Allergy. 2004 Apr;34(4):583-90. doi: 10.1111/j.1365-2222.2004.1923.x.
7
Detection of Circulating Peanut Components in Serum after Ingestion.食用花生后血清中花生成分的检测。
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8
Soy Gly m 8 sIgE Has Limited Value in the Diagnosis of Soy Allergy in Peanut Ara h 2-Sensitized Adults.大豆 Gly m 8 sIgE 在诊断花生 Ara h 2 敏感成人的大豆过敏方面价值有限。
Int Arch Allergy Immunol. 2023;184(8):767-775. doi: 10.1159/000530026. Epub 2023 Apr 18.
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Ara h 2 and Ara 6 are the best predictors of severe peanut allergy: a double-blind placebo-controlled study.Ara h 2 和 Ara 6 是严重花生过敏的最佳预测因子：一项双盲安慰剂对照研究。
Allergy. 2015 Oct;70(10):1239-45. doi: 10.1111/all.12671. Epub 2015 Jul 1.
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The combination of Ara h 2-sIgE and basophil activation test could be an alternative to oral food challenge in cases of suspected peanut allergy.在疑似花生过敏的情况下，Ara h 2-sIgE 与嗜碱性粒细胞活化试验的联合应用可能是口服食物激发试验的替代方法。
Pediatr Allergy Immunol. 2023 Aug;34(8):e14007. doi: 10.1111/pai.14007.

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Prediction of pediatric peanut oral food challenge outcomes using machine learning.使用机器学习预测儿科花生口服食物激发试验结果
J Allergy Clin Immunol Glob. 2024 Apr 7;3(3):100252. doi: 10.1016/j.jacig.2024.100252. eCollection 2024 Aug.
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A Food Matrix Triggers a Similar Allergic Immune Response in BALB/c Mice Sensitized with Native, Denatured, and Digested Ovalbumin.食物基质在经天然、变性和消化的卵清蛋白致敏的BALB/c小鼠中引发相似的过敏免疫反应。
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Diagnostic utility of allergy tests to predict baked egg and lightly cooked egg allergies compared to double-blind placebo-controlled food challenges.
过敏原检测对预测烘焙鸡蛋和轻度烹饪鸡蛋过敏的诊断效用与双盲安慰剂对照食物激发试验的比较。
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The Very Low IgE Producer: Allergology, Genetics, Immunodeficiencies, and Oncology.极低IgE产生者：过敏学、遗传学、免疫缺陷与肿瘤学
Biomedicines. 2023 May 6;11(5):1378. doi: 10.3390/biomedicines11051378.