Department of Obstetrics and Gynecology, Michigan Medicine, Ann Arbor, Michigan, USA.
University of Michigan Medical School, Ann Arbor, Michigan, USA.
Int J Gynaecol Obstet. 2022 Dec;159(3):743-750. doi: 10.1002/ijgo.14162. Epub 2022 Mar 14.
To determine the implications of an incidentally noted subchorionic hematoma on pregnancy outcomes in the infertile population.
Retrospective cohort study at a tertiary care, university-based facility. All patients with intrauterine pregnancy on initial obstetric ultrasound presenting to an infertility clinic between January 2015 and March 2018 (n = 1210), regardless of treatment cycle, were included. Nonviable pregnancies were excluded. The main outcome measured was association between subchorionic hematoma and first trimester miscarriage.
The prevalence of subchorionic hematoma was 12.5% (n = 151) and did not differ by type of fertility treatment. There was no association between subchorionic hematoma and first trimester miscarriage; however, among patients with subchorionic hematoma, those who reported both bleeding and cramping had an increased probability of miscarriage compared to those without symptoms (0.62 vs. 0.12, P <0.001). The live birth rate in this sample was 81.3% and there were no statistically significant differences in pregnancy outcomes between those with and without subchorionic hematoma.
Among an infertile population, there was no increased risk of miscarriage when subchorionic hematoma was seen on early ultrasound; however, when patients noted both vaginal bleeding and cramping, their probability of miscarriage was significantly increased.
确定在不孕人群中偶然发现的绒毛膜下血肿对妊娠结局的影响。
这是在一家三级保健、以大学为基础的机构进行的回顾性队列研究。纳入 2015 年 1 月至 2018 年 3 月期间在不孕诊所就诊的所有在初始产科超声检查中发现宫内妊娠的患者(n=1210),无论治疗周期如何。排除不可存活的妊娠。主要结局指标是绒毛膜下血肿与早期流产之间的关系。
绒毛膜下血肿的患病率为 12.5%(n=151),与生育治疗类型无关。绒毛膜下血肿与早期流产之间无关联;然而,在有绒毛膜下血肿的患者中,报告既有出血又有痉挛的患者流产的可能性高于无症状的患者(0.62 比 0.12,P<0.001)。该样本的活产率为 81.3%,有和没有绒毛膜下血肿的患者在妊娠结局方面没有统计学上的显著差异。
在不孕人群中,早期超声检查发现绒毛膜下血肿并不会增加流产的风险;然而,当患者出现阴道出血和痉挛时,其流产的可能性显著增加。