比较肾移植和血液透析患者的左心房变形参数。
Comparison of left atrial deformation parameters between renal transplant and hemodialysis patients.
机构信息
Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
Department of Nephrology, Faculty of Medicine, Ondokuz Mayis University, Samsun, Turkey.
出版信息
Cardiovasc Ultrasound. 2022 Feb 25;20(1):5. doi: 10.1186/s12947-022-00275-4.
BACKGROUND
Renal transplantation (RT) has been demonstrated to improve left ventricular systolic function. However, only few studies have attempted to reveal the effects of transplantation on left atrial (LA) function. In our study, we aimed to compare LA function between RT and hemodialysis patients.
METHODS
This cross-sectional study included 75 consecutive patients with RT, and 75 age- and gender-matched patients on maintenance hemodialysis. LA strain and strain rate (SR) analyzed by two-dimensional (2D) speckle tracking echocardiography (STE) were compared between the groups in addition to standard echocardiographic parameters.
RESULTS
LA strain during reservoir phase (29.88 ± 5.76% vs 26.11 ± 5.74%, P < .001), LA strain during conduit phase (- 15.28 ± 5.00% vs - 12.92 ± 4.38%, P = .003), and LA strain during contraction phase (- 14.60 ± 3.32% vs - 13.19 ± 3.95%, P = .020) were higher in the transplantation group. Similarly, LA peak SR during reservoir phase (1.54 ± 0.33 s vs 1.32 ± 0.33 s, P < .001), LA peak SR during conduit phase (- 1.47 ± 0.49 s vs - 1.12 ± 0.42 s, P < .001), and LA peak SR during contraction phase (- 2.13 ± 0.46 s vs - 1.83 ± 0.58 s, P = .001) were higher in the transplantation group as well.
CONCLUSIONS
LA function assessed by 2D STE was better in RT patients than hemodialysis patients. This may suggest favorable effects of RT on LA function.
背景
肾移植（RT）已被证明可改善左心室收缩功能。然而，只有少数研究试图揭示移植对左心房（LA）功能的影响。在我们的研究中，我们旨在比较 RT 和血液透析患者的 LA 功能。
方法
这项横断面研究纳入了 75 例连续的 RT 患者和 75 例年龄和性别匹配的维持性血液透析患者。除了标准的超声心动图参数外，我们还比较了两组的二维（2D）斑点追踪超声心动图（STE）分析的 LA 应变和应变率（SR）。
结果
RT 组的 LA 储液期应变（29.88 ± 5.76% vs 26.11 ± 5.74%，P < 0.001）、LA 传导期应变（-15.28 ± 5.00% vs -12.92 ± 4.38%，P = 0.003）和 LA 收缩期应变（-14.60 ± 3.32% vs -13.19 ± 3.95%，P = 0.020）较高。同样，RT 组的 LA 峰值储液期 SR（1.54 ± 0.33 s vs 1.32 ± 0.33 s，P < 0.001）、LA 峰值传导期 SR（-1.47 ± 0.49 s vs -1.12 ± 0.42 s，P < 0.001）和 LA 峰值收缩期 SR（-2.13 ± 0.46 s vs -1.83 ± 0.58 s，P = 0.001）也较高。
结论
2D STE 评估的 LA 功能在 RT 患者中优于血液透析患者。这可能表明 RT 对 LA 功能有有利影响。
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