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台湾地区可电击心律的院外心脏骤停的特征、预后因素及时间趋势——一项7年的观察性研究

Characteristics, prognostic factors, and chronological trends of out-of-hospital cardiac arrests with shockable rhythms in Taiwan - A 7-year observational study.

作者信息

Chi Chien-Yu, Chen Yen-Pin, Yang Chih-Wei, Huang Chien-Hua, Wang Yao-Chang, Chong Kah-Meng, Wang Hui-Chih, Lien Wan-Ching, Yang Mei-Fen, Ma Matthew Huei-Ming, Huang Chien-Hua, Chen Zheng-Cheng, Ko Patrick Chow-In

机构信息

Department of Emergency Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin County, Taiwan.

Department of Emergency Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

出版信息

J Formos Med Assoc. 2022 Oct;121(10):1972-1980. doi: 10.1016/j.jfma.2022.01.024. Epub 2022 Feb 23.

Abstract

BACKGROUND

The study aimed to explore the characteristics, predictors, and chronological trends of outcomes for adult out-of-hospital cardiac arrests (OHCAs) with shockable rhythms.

METHODS

A 7-year, community-wide observational study using an Utstein-style registry was conducted. Patients who were not transported, those who experienced trauma and those who lacked electronic electrocardiography data were excluded; those with initial shockable rhythms of ventricular fibrillation (VF) or pulseless ventricular tachycardia (pVT) were included. Outcomes were survival of discharge (SOD) and favorable neurological status (CPC 1-2). The outcome predictors, chronological trends, and their relationship with system interventions were analyzed.

RESULTS

Of the 1544 shockable OHCAs (incidence 12.6%) included, 97.6% had VF and 2.4% had pVT. VF showed better outcomes than pVT. Predictors for both outcomes (SOD; CPC 1-2) were chronological change (adjusted odds ratio [aOR]: 1.133; 1.176), younger age (aOR: 0.973; 0.967), shorter response time (aOR: 0.998; 0.999), shorter scene time (aOR: 0.999; 0.999), witnessed collapse (aOR: 1.668; 1.670), and bystander cardiopulmonary resuscitation (BCPR) (aOR: 1.448; 1.576). Predictors for only SOD were public location (aOR: 1.450) and successful prehospital defibrillation (aOR: 3.374). The use of the supraglottic airway was associated with adverse outcomes. Chronologically with system interventions, BCPR rate, the proportion of shockable OHCA, and improved neurological outcomes increased over time.

CONCLUSION

The incidence of shockable OHCA remained low in Asian community. VF showed better outcomes than pVT. Over time, the incidence of shockable rhythm, BCPR rate and patient outcomes did improve with health system interventions. The number of prehospital defibrillations did not predict outcomes.

摘要

背景

本研究旨在探讨伴有可电击心律的成人院外心脏骤停(OHCA)的特征、预测因素及时间趋势。

方法

采用Utstein式登记系统进行了一项为期7年的社区范围观察性研究。排除未转运患者、经历创伤的患者以及缺乏电子心电图数据的患者;纳入初始心律为心室颤动(VF)或无脉性室性心动过速(pVT)的可电击心律患者。结局指标为出院存活(SOD)和良好神经功能状态(CPC 1 - 2)。分析了结局预测因素、时间趋势及其与系统干预的关系。

结果

纳入的1544例可电击OHCA(发生率12.6%)中,97.6%为VF,2.4%为pVT。VF的结局优于pVT。两种结局(SOD;CPC 1 - 2)的预测因素为时间变化(调整优势比[aOR]:1.133;1.176)、年龄较小(aOR:0.973;0.967)、反应时间较短(aOR:0.998;0.999)、现场时间较短(aOR:0.999;0.999)、目睹心脏骤停(aOR:1.668;1.670)和旁观者心肺复苏(BCPR)(aOR:1.448;1.576)。仅SOD的预测因素为公共场所(aOR:1.450)和院前除颤成功(aOR:3.374)。声门上气道的使用与不良结局相关。随着时间推移及系统干预,BCPR率、可电击OHCA的比例和改善的神经学结局均有所增加。

结论

亚洲社区可电击OHCA的发生率仍然较低。VF的结局优于pVT。随着时间推移,可电击心律的发生率、BCPR率和患者结局确实因卫生系统干预而有所改善。院前除颤次数不能预测结局。

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